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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

Applying a specific inhibitor lightens skin and hair color.

Chemotherapy can cause permanent, non-reversible hair loss similar to pattern baldness.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Thyroid function affects skin health, with a complex interaction between the two.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.

Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.

Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Most skin changes during pregnancy go away after giving birth.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

IGF-1 increases whisker growth in transgenic mice.

Pannexin 3 is important for bone formation and the development of bone cells.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.