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The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.

Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.

Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Women may need different blood pressure guidelines than men for heart disease prevention.

The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

Moxibustion may help improve ovarian function by changing androgen levels.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Different PCOS subgroups have similar metabolic features, but those without menstrual problems have milder issues.

PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Mutations in certain receptors can cause diseases and offer new treatment options.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.