59 citations
,
March 2020 in “Journal of Biomedical Science” This study explored the complex roles of niche cells in regulating hair follicle stem cells, identifying specific cell functions such as signaling, sensing, and relaying messages, which could provide insights into treating hair loss conditions like androgenetic alopecia and alopecia areata.
This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.
111 citations
,
November 2010 in “Human Reproduction” This study found that young indigenous South Asian women with polycystic ovary syndrome are more likely to be centrally obese and have metabolic syndrome, particularly with increasing age, higher BMI, and acanthosis nigricans.
June 1995 in “International Journal of Gynecology & Obstetrics” This article lacks an abstract and reports no new findings.
June 2007 in “Endocrinology and Metabolism Clinics of North America” This study reports that incomplete information in a reverse supply chain can lead to efficiency losses, but a two-part tariff contract for the remanufacturer may improve performance by eliciting private information from collectors.
37 citations
,
January 2004 in “Hormone Research in Paediatrics” In this study, the prevalence of clinical polycystic ovary syndrome among high school girls in Isfahan, Iran was reported at 3%, with a note that hormonal assessments might uncover higher rates.
6 citations
,
December 2021 in “International Journal of Endocrinology” This study found that the INSR His1058 C/T SNP does not increase the risk of developing PCOS among Kashmiri women.
3 citations
,
July 2007 in “Endocrine updates” PCOS leads to various immediate and long-term health problems, affecting quality of life and increasing costs.
August 2025 in “Obstetrics and gynecology.” This article reviews the management of polycystic ovarian syndrome, highlighting lifestyle modification and individualized pharmacological treatment strategies, and reports no new clinical results.
May 2022 in “Endocrine practice” This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.
April 2026 in “International Journal of Impotence Research” This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.
August 2020 in “International research journal of pharmacy” This study found that lifestyle interventions, along with regular medication, improved the quality of life for women with PCOS.
414 citations
,
August 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study estimates the total cost of evaluating and treating polycystic ovary syndrome in reproductive-aged women in the United States to be $4.36 billion, suggesting more liberal screening could be beneficial.
89 citations
,
March 2001 in “Endocrine practice” This article provides diagnosis and treatment guidelines for hyperandrogenic disorders in women but reports no new clinical results; it offers a summary of accepted scientific information and suggestions for clinical practice.
16 citations
,
December 2007 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the impact of polycystic ovary syndrome on health-related quality of life, highlighting its negative effects which may be influenced by cultural perceptions, obesity, infertility, and menstrual issues.
15 citations
,
March 1997 in “International Journal of Dermatology” This article discusses the potential use of 5α-reductase inhibitors in dermatology and reports no new clinical results; the authors suggest further exploration of their dermatological applications.
2 citations
,
January 2017 in “Annals of Dermatology” Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.
2 citations
,
September 2016 in “Journal of evolution of medical and dental sciences” This study found that patients with thyroid dysfunction were more likely to experience skin disorders such as chronic idiopathic urticaria, vitiligo, and alopecia areata compared to a control group.
1 citations
,
January 2022 in “Journal of experimental and clinical medicine” This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.
January 2025 in “Journal of Men s Health” This article reports that the rise in erectile dysfunction among young men may be linked to mental health issues and societal pressures, with online communities often encouraging risky substance use like anabolic steroids and finasteride, which can exacerbate psychological and physical health problems.
This review discusses polycystic ovary syndrome, highlighting its associations with hyperandrogenism, chronic anovulation, polycystic ovaries, and increased risks of infertility and metabolic disorders, and reports no new clinical results.
1 citations
,
July 2025 in “Middle East Fertility Society Journal” This study found that women with PCOS had significantly higher levels of several autoantibodies compared to healthy controls, suggesting a potential autoimmune component to PCOS that might aid in better disease characterization and personalized management.
This study found that expert consensus endorsed myo-inositol, alone or combined with folic acid and vitamin D₃, as an effective, well-tolerated option for managing acne and hirsutism in PCOS.
1744 citations
,
August 2006 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.
947 citations
,
February 2004 in “The Journal of Clinical Endocrinology and Metabolism” In this study, polycystic ovary syndrome was the most prevalent cause of androgen excess, and suppressive hormonal therapy improved hirsutism, menstrual dysfunction, and acne in most patients, though side effects were common.
121 citations
,
April 2008 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” In this study, the prevalence of polycystic ovary syndrome in southern China was found to be 2.2%, with affected women showing distinct metabolic and hormonal characteristics compared to others.
91 citations
,
December 2017 in “Systems Biology in Reproductive Medicine” This meta-analysis found that lower serum SHBG levels are associated with an increased risk of PCOS, and improving SHBG levels through treatment may reduce PCOS complications.
74 citations
,
July 2010 in “The Journal of Clinical Endocrinology & Metabolism” This study found that gonadal dysfunction is very common in premenopausal women with acromegaly and may be caused by hyperprolactinemia, GH/IGF-I excess, or tumor effects.
58 citations
,
November 2020 in “International Journal of Molecular Sciences” This review discusses the relationship between SHBG, NAFLD, and PCOS and reports no new clinical results; the authors highlight low hepatic SHBG production as potentially significant in PCOS pathogenesis.
51 citations
,
November 2011 in “Reproductive Biology and Endocrinology” In this study of reproductive-aged women in Tehran, idiopathic hirsutism and polycystic ovary syndrome were reported to be prevalent, with rates influenced by the screening methods used.