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Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Testosterone may slow down wound healing and increase inflammation.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.