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Modified PRP therapy successfully treated severe alopecia unresponsive to traditional methods.

Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.

Severe hair loss significantly worsens quality of life.

Wearing headcovers doesn't affect male-pattern hair loss severity.

Women have unique stroke risks due to hormones, contraceptives, pregnancy, and menopause.

The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Hormonal implants have many side effects that often outweigh their benefits.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.