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New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Mice with human skin protein K8 had more skin problems and cancer.

Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Androgens can both increase body hair and cause scalp hair loss.

Akt2 protein is essential for normal cell division in early mouse embryos.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.