research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
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research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Involvement of Wnt, Eda, and Shh at Defined Stages of Sweat Gland Development
Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.
research Responses of Hair Follicle–Associated Structures to Loss of Planar Cell Polarity Signaling
Loss of Fz6 disrupts hair follicle and associated structures' orientation.
research Perspectives and Challenges of Hair Analysis
Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Non-Edg Family LPA Receptors: The Cutting Edge of LPA Research
New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
research Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits
Melatonin given to pregnant rabbits improved their babies' fur quality.
research Skin Cancer in Skin of Color Transplant Patients
Non-white organ transplant patients have worse skin cancer outcomes due to later diagnosis and treatment.
research 3D Imaging of Cleared Ex Vivo Normal Human Skin, Skin Appendages, and Psoriasiform Skin Lesion Using Light-Sheet Microscopy
The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.
research Dermatomyositis-Related Panniculitis of the Neck
A woman with dermatomyositis improved after treatment for neck panniculitis, suggesting similar treatment for related conditions.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research Design of a RADA16-Based Self-Assembling Peptide Nanofiber Scaffold for Biomedical Applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Efficacy of an Agonist of α-MSH, the Palmitoyl Tetrapeptide-20, in Hair Pigmentation
Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
research Characterization of a Mouse Scube3 Reporter Line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research A Dietary Supplement Improves Age-Related Dermatological Changes: Observational, Anecdotal, Spontaneous Study
The dietary supplement significantly improved skin, nails, and hair in older adults.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Molecular Biology of Hair Morphogenesis: Development and Cycling
Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
research Transcutaneous Implantation of Valproic Acid-Encapsulated Dissolving Microneedles Induces Hair Regrowth
Tiny needles with valproic acid can effectively regrow hair.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment
Various treatments exist for hair loss, but more research is needed for better options.
research Biotinidase Deficiency Characterized by Skin and Hair Findings
Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
research Itpr3 Is Responsible for the Mouse Tufted (tf) Locus
The Itpr3 gene causes a specific hair pattern in mice.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Cosmetic Procedures in the Treatment of Alopecia
Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.