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In this study, researchers examined androgen receptor activity in the adult mouse brain and found specific expression in key brain areas, which could inform understanding of cognitive side effects in humans undergoing androgen deprivation therapy for prostate cancer.

Innovative methods are reducing animal testing and improving biomedical research.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.

This study found that keratin-associated proteins related to metallothionein and occludin appear in various animals, suggesting they may have roles beyond hair characteristics and were later adapted for hair production.

This review discusses autoimmune blistering diseases across species and highlights new treatment efficacy findings and ongoing trials, but it reports no new clinical results.

This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.

This study found that obesity in women may impair endometrial stromal function and contribute to reproductive complications, possibly due to metabolic influences rather than immune cell differences.

This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.

This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

This article discusses themes in the molecular structure of hair and reports no new research findings.

This study suggests that hair follicle dermal stem/progenitor cells play a key role in both hair regeneration and skin wound healing, with potential implications for preventing hair follicle miniaturization linked to aging or alopecia.

This review discusses recent advancements in hair follicle regeneration technologies, including the authors' own development of functional hair regeneration through bioengineered follicle germ transplantation, but reports no new clinical results.

This review analyzes the reported prevalence of polycystic ovary syndrome (PCOS) based on different diagnostic criteria but does not provide new clinical results.

This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.

This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

In this study, the prevalence of polycystic ovary syndrome among Han Chinese women aged 19-45 was found to be 5.6%, and PCOS was associated with increased metabolic risks, particularly in obese individuals.

This review discusses the expression patterns and biochemical roles of Msx and Dlx genes during development but does not present new research findings.

Androgens can cause hair growth in some areas and hair loss on the scalp.

This study found that hair follicles in both mice and humans may serve as an important site for melatonin synthesis and signaling, potentially influencing hair cycle regulation by modulating keratinocyte apoptosis.

This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.

This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.

This study suggests that miniaturization in pattern hair loss may occur abruptly and can be reversed with treatment, as supported by histologic evidence in finasteride-responsive patients.

This study identified a genetic locus associated with idiopathic scoliosis in females, which might influence spinal gene expression and was previously linked to protection from early-onset alopecia.

This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.

This article reviews management strategies for PCOS and reports no new clinical results; the authors highlight oral contraceptives, lifestyle modifications, and metformin as key interventions.

This review discusses the dermatologic manifestations of hyperandrogenism in women and outlines the diagnostic approach and treatment options, reporting no new clinical results.

This article explores how extrafollicular environments and stem cell configurations influence hair and feather regeneration but provides no new experimental results.