March 2026 in “Folia Histochemica et Cytobiologica” This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.
This study found that Ca²⁺ signaling and peptidylarginine deiminase enzymes play a crucial role in activating neural stem cells in response to injury in zebrafish, suggesting potential therapeutic targets for CNS injuries and cancer.
January 2026 in “Frontiers in Medicine” This study found that acupuncture may reduce anxiety and depression in women with polycystic ovary syndrome, potentially through hormonal and neuroendocrine modulation, but further high-quality research is needed to confirm these findings.
January 2026 in “Forum Dermatologicum” This review analyzed scientific literature and found that dermatological symptoms, such as hirsutism and acne, frequently appear as early indicators of PCOS, reflecting hormonal imbalances and aiding diagnosis of the disorder.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
December 2025 in “Journal of AI” This study bibliometrically evaluated 5741 articles on PRP from 1980 to 2024, highlighting Türkiye's contribution and identifying prominent research areas such as orthopedics and wound healing.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that a combination of five medicinal plants traditionally used in Chinese medicine significantly improved skin repair and delayed aging markers in laboratory models, suggesting synergistic anti-aging effects over individual ingredients.
November 2025 in “Fertility Gynecology and Andrology” This study highlights that polycystic ovary syndrome develops through genetic and environmental factors, with insulin resistance as a key mechanism, impacting the risk of metabolic and cardiovascular conditions.
January 2025 in “Directory of Open access Books (OAPEN Foundation)” This book reviews the symptoms, diagnosis, and treatments for Polycystic Ovary Syndrome, providing a comprehensive exploration but reports no new clinical results.
March 2024 in “Frontiers in reproductive health” This study explored how an educational intervention on reducing phthalate exposure through hair care product choices influenced the hair care practices of pregnant women of color, identifying key life stages and themes related to these practices, including cultural influences, product impacts, and individual autonomy.
December 2023 in “Anti-Aging Eastern Europe” This review discusses the interplay between polycystic ovary syndrome, aging, and fertility in women, and reports no new clinical results; the authors highlight pathways and interventions needing further research.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.
September 2023 in “Frontiers in cell and developmental biology” This study found that a catalytically active version of Vav2 significantly altered gene expression patterns in hair follicle stem cells in mice, with these changes varying over the animals' lifespans.
September 2023 in “Research Square (Research Square)” In this study, overweight women with polycystic ovarian syndrome who took evening primrose oil for 10 weeks experienced significant reductions in BMI, LDL, and total cholesterol levels, alongside hormonal changes such as decreased LH, FSH, and testosterone levels, and increased estrogen.
August 2023 in “Research Square (Research Square)” This study found that two microRNAs, oar-miR-23b and oar-miR-133, inhibit the development of hair follicles in superfine wool sheep by targeting genes involved in key signaling pathways, suggesting their potential use as molecular markers for breeding fine wool sheep.
February 2023 in “Acta Scientific Women s Health” This review examines emerging and past therapies for recurrent implantation failure, focusing on three innovative strategies: PBMC, G-CSF, and PRP, but reports no new clinical results.
September 2022 in “Research Square (Research Square)” This study found that overexpressing Rps14 in supporting cells promoted hair cell regeneration in the organ of Corti by facilitating cell proliferation and differentiation.
July 2022 in “Research Square (Research Square)” This study found that miR-23b and miR-133 significantly reduce mRNA and protein levels of specific target genes involved in Merino sheep hair follicle development, providing insight into molecular breeding for fine wool production.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that intracrine androgen signaling, mediated by steroid 5α-reductase, is essential for optimal decidualization and vascular development in the endometrium during pregnancy, indicating potential targets for improving age-related fertility issues.
February 2022 in “Research Square (Research Square)” This study identified candidate genes related to hair follicle development in Merino sheep, providing insights for improving sheep wool quality and potentially understanding human hair growth mechanisms.
This genetic study identified a potential interval for the Marie Unna hypotrichosis gene but found no mutations in the nearby hr gene, suggesting its involvement remains unconfirmed.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
January 2020 in “Research Portal Denmark” This study concludes that anti-androgenic chemicals causing short anogenital distance in male fetuses also induce a feminized transcriptional profile in the perineum, implicating Wnt and estrogen signaling in the process.
This review discusses the diagnostic criteria and management challenges for polycystic ovarian syndrome and reports no clinical results, highlighting complications associated with pregnancy in women with the condition.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses the interplay between signaling/transcription factor-mediated and epigenetic mechanisms in skin development and regeneration, highlighting the need for further exploration of epigenome reorganization in these processes.
This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.
April 2017 in “Journal of Pharmaceutical Investigation” In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.