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Methotrexate may effectively and safely treat hair loss in children, with notable improvement after 12-15 months.

Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.

Using hair loss drugs finasteride and dutasteride may cause sexual side effects.

Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.

A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Docetaxel is safe and works well for older people with cancer, with manageable side effects.

Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.

Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.

JAK-inhibitors for alopecia areata are generally safe with mostly mild side effects and a low rate of treatment withdrawal.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Kawasaki's disease can occur in adults and should be considered with specific symptoms and high ferritin levels.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Traditional Chinese medicines with heavy metals can cause severe poisoning.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

Finasteride may help some women with hair loss, but better options exist.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Pregnancy with Cushing's syndrome is rare and risky for both mother and baby, needing early diagnosis and treatment.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.