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Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Prolactin slows down hair growth in mice.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.