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Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

The patient improved after antiviral treatment for a viral infection.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Special fiber materials boost the healing properties of certain stem cells.

Oral isotretinoin for severe acne can change hormone levels but does not significantly affect ovarian function.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.