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The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Cell aging can be both good and bad for tissue repair.

IGF-1 increases whisker growth in transgenic mice.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Hair follicles are valuable for regenerative medicine and wound healing.

Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.