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This study found that the transcription factor FOXO1 plays a crucial role in wound healing by protecting keratinocytes from oxidative stress and regulating TGF-β expression.

This study found no support for the idea that male-pattern baldness in female-to-male transsexuals indicates an increased risk of coronary heart disease through androgenic effects on classic risk factors.

This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.

This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.

This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.

Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.

This review discusses the interplay between epilepsy and reproductive endocrine disorders, examining the factors involved and emphasizing the importance of monitoring but reports no new research findings.

This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.

This review discusses the skin manifestations of endocrine diseases and reports no new clinical findings, emphasizing the importance of recognizing these signs for early diagnosis.

This review discusses the management of polycystic ovary syndrome in women and reports no new clinical results.

This meta-analysis reviewed 25 studies and suggested that herbal interventions could improve reproductive health in women with PCOS, showing benefits across measures such as Body Mass Index, hirsutism, and insulin levels, although results were mixed for fasting glucose and FSH levels.

This study found a significant association between the IRS-2 gene variant and an increased risk of PCOS, especially in non-obese women in the Chinese population from Taiwan.

This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.

This study reports an increased frequency of the DI genotype of the ACE gene polymorphism among women with PCOS, notably in those with hyperandrogenism, and an association of the II genotype with insulin resistance.

This study suggests that insulin levels may influence ovarian volume in women with idiopathic hirsutism who have normal ovulatory cycles and androgen levels.

This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.

This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.

This study reported that visceral massage improved skin elasticity and metabolic indicators such as glucose and lipid levels, suggesting its potential as a non-invasive method for enhancing skin health and systemic metabolism.

In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.

The researchers reported a high incidence of hyperuricemia in women with PCOS, with positive correlations to testosterone, SHBG, HOMA-IR, and LDL levels, but negative correlations to HbA1C, FPG, and FSI.

This study reports that an intervention decreased glucose and insulin levels, indicating improved insulin resistance, which is linked to a skin condition called acne vulgaris and other disorders associated with insulin resistance.

This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.

This study found that BMI was the only significant predictor of elevated androgen levels in adolescents with PCOS, and hyperandrogenemia was not linked to a specific PCOS phenotype.

This study found that serum vaspin levels were elevated in women with polycystic ovary syndrome compared to controls, but treatment with metformin or weight loss did not significantly change these levels.

This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.

This study found that serum cystatin C levels may be elevated in adolescent females with PCOS, suggesting it could serve as a predictive marker for metabolic and cardiovascular issues independent of renal function.

This study found that women with polycystic ovary syndrome have elevated cardiovascular risk markers, with levels being higher in obese participants compared to non-obese participants.

This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.

This study found that long-term dutasteride therapy in men with benign prostatic hyperplasia worsened erectile dysfunction, reduced testosterone levels, and increased blood glucose and lipid profile, indicating negative metabolic impacts.

This study found that women with polycystic ovary syndrome have higher serum VEGF-B levels, which are linked to insulin resistance and decrease after metformin treatment.