3 citations
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January 2020 in “Indian Dermatology Online Journal” In this study, significant correlations were observed between acanthosis nigricans and factors like free testosterone, DHEAS, fasting blood sugar, and BMI, as well as between hirsutism and elevated DHEAS, free testosterone, and BMI among patients with polycystic ovarian disease.
January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
December 2022 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism” This study found a significant association between early onset androgenetic alopecia and metabolic syndrome, with higher prevalence of metabolic risk factors in affected individuals compared to a control group.
4025 citations
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December 2003 in “Human Reproduction” This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
July 2020 in “International Journal of Research” This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.
This study found that elevated serum alarin levels in men with androgenetic alopecia may be linked to the presence of metabolic syndrome, correlating with the condition's severity and duration.
39 citations
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August 2001 in “Clinical endocrinology” This study found that lean women with PCOS have a similar degree of tissue insulin resistance as obese women with PCOS, suggesting that insulin resistance may be a primary feature of the syndrome.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case presentation highlights a 26-year-old woman with PCOS, metabolic syndrome, and prediabetes, emphasizing the importance of early recognition and multidisciplinary management to prevent long-term metabolic complications.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case study details a 26-year-old woman diagnosed with PCOS and metabolic syndrome, highlighting the importance of early recognition and multidisciplinary management to improve reproductive and metabolic health outcomes.
26 citations
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January 2000 in “Hormone research in paediatrics” This review discusses the relationship between hyperandrogenism and insulin resistance in PCOS, focusing on insulin dynamics, molecular mechanisms, genetic studies, and potential long-term treatments, but presents no new clinical results.
2 citations
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March 2018 in “INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY” This case report describes a pregnant woman diagnosed with Cushing Syndrome, likely due to an adrenal tumor, whose condition worsened during hospitalization, resulting in heart failure, sepsis, and shock.
March 2023 in “Journal of Education, Health and Sport” Among women with polycystic ovary syndrome, this study observed a median depression incidence of 36.6%, significantly higher than the 14.2% reported in women without the syndrome.
March 2023 in “Scholars international journal of obstetrics and gynecology” This article reviews the metabolic and endocrine complexities of PCOS, emphasizing the importance of lifestyle changes and medical management in addressing its various symptoms and complications, but reports no new clinical results.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
December 2025 in “Medicine” This study suggests potential causal links between blood levels of glutamine, citric acid, glucose, various lipids, and lipoproteins with alopecia areata, finding glutamine may have a protective effect and noting no evidence of reverse causality. Further research is needed to validate these associations.
29 citations
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January 2009 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have significantly higher plasma levels of thrombin-activatable fibrinolysis inhibitor and other hemostatic markers compared to age- and BMI-matched healthy controls.
3 citations
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December 2016 in “PubMed” This study found that PCOS patients with menstrual disorders exhibited hormonal changes and higher fasting glucose levels, despite no significant differences in insulin resistance markers.
October 2023 in “Benha Journal of Applied Sciences” In this study, patients with androgenic alopecia were found to have higher levels of insulin, glucose, and HOMA-IR compared to healthy individuals, suggesting distinct metabolic profiles that may contribute to the condition's development.
May 2023 in “Research Square (Research Square)” In this study, researchers observed that treatment with Agaricus subrufescens ethanolic extract improved blood glucose, testosterone levels, and menstrual irregularity in rat models of letrozole-induced Polycystic Ovarian Syndrome, also noting a decrease in elevated liver and ovary weights, suggesting protective effects on renal function.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
This study found that women with PCOS had significant hormonal imbalances, increased central obesity, and a lower 2D:4D digit ratio, suggesting prenatal androgen exposure may play a role in the condition's development.
January 2017 in “Journal of clinical & experimental dermatology research” This report describes a case of HAIR-AN syndrome in a young woman, characterized by acanthosis nigricans, insulin resistance, and polycystic ovaries, highlighting its rarity and multisystem nature.
23 citations
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March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
3 citations
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January 2013 in “Egyptian Liver Journal” In this study, researchers found a significant prevalence of nonalcoholic fatty liver disease in Egyptian women with polycystic ovary syndrome, with insulin resistance being a key predictive factor.
February 2005 in “Journal of The American Academy of Dermatology” This discussion covers various nail disorders, including tumors and non-neoplastic issues, emphasizing that not all nail abnormalities are due to fungal infections, but it reports no new clinical findings.
20 citations
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August 2022 in “Archives of Medical Science” This publication discusses the 2021 ESC Guidelines for the prevention of cardiovascular disease in clinical practice and reports no new results.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
January 2026 in “Journal of Clinical Medicine” This review identified significant associations between glucose dysregulation and various dermatological conditions like psoriasis and acne, suggesting that dietary interventions and probiotics may help manage related inflammation, highlighting the need for holistic treatment approaches for insulin resistance and metabolic syndrome.
In this study, testosterone treatment was found to increase blood pressure in rats, potentially through mechanisms involving sodium and water retention in the kidneys and changes in specific gene expressions in the brain.