research Anti-Ku Antibodies: Much More Than Scleromyositis
Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.
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research Diagnosis and Treatment of Demodicosis with Secondary Bacterial Infection in a Pug: A Case Presentation
A Pug with skin issues was successfully treated for mite and bacterial infections.
research Testosterone Secreting Ovarian Tumor: A Rare Cause of Erythrocytosis and Pulmonary Embolus
A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research Hyperandrogenism Caused by Leydig Cell Tumor of the Ovary
A woman's excess male hormone symptoms were caused by a rare benign tumor in her ovary.
research Molecular Genetic Dissection of ILVEN Leads to Successful Targeted Therapy
Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.
research Association Between Hair Proliferation and Flavonoid Silibinin in Human Dermal Papilla Cells
Silibinin may help promote hair growth and treat hair loss.
research An Unusual but Important Cause of Hyperandrogenism in Women
A woman's high testosterone levels were caused by a rare ovarian tumor, not the initially diagnosed condition.
research An Integrated Model of Alopecia Areata Biomarkers Highlights Both Th1/Th2 Upregulation, with Stronger Correlations Between Th2 Activation and Disease Severity
Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
research Disorders in Male Sexual Differentiation Due to 5α-Reductase-2 Deficiency
5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
research Virilizing Adrenocortical Oncocytoma in a Toddler
A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.
research Decision Letter: Human Biallelic MFN2 Mutations Induce Mitochondrial Dysfunction, Upper Body Adipose Hyperplasia, and Suppression of Leptin Expression
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
research Acanthosis Nigricans During HAIR-AN Syndrome: The Tree That Hides the Forest
The case shows skin changes can indicate deeper health issues like insulin resistance, which are challenging to manage.
research Targeting mTORC1 Suppresses Proliferation of Keratinocyte Stem Cells and Inhibits Skin Tumor Promotion in Mice
Blocking mTORC1 reduces skin tumor growth in mice.
research Virilization in a Postmenopausal Woman: Ovarian Leydig Cell Tumor
A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
research Hyperandrogenism After Menopause
A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
research Pituitary-Dependent Hyperadrenocorticism in a Shi Tzu Dog Treated with Twice-Daily Oral Trilostane: A Case Report
A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.
research It's Not Like Growing Grass
Blocking a compound called prostaglandin D₂ might help treat hair loss.
research Sunitinib
A woman got male pattern baldness from touching her husband's testosterone gel.
research Clinical Study of Androgenic Alopecia in 148 Patients
Family history affects onset and severity of androgenic alopecia, but treatment success depends more on therapy duration.
research The Potential of Circulating Endothelial Cells as Prognostic Biomarkers in Prostate Cancer
CEC levels may be a useful marker for predicting prostate cancer progression.
research 66-Year-Old Woman With Painless Vesicular Lesions
A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities
Most women with excessive hair growth have a hormonal cause.
research The HAIR-AN Syndrome: A Case Report
Treatment improved symptoms in a woman with HAIR-AN syndrome.
research A Case Report of Cushing's Syndrome Due to an Adrenal Carcinoma
A woman's Cushing's syndrome caused by adrenal cancer improved after surgery.
research Is Early Onset Androgenetic Alopecia Related to Hyperuricemia? A Case Control Study
Men with early onset hair loss are more likely to have high uric acid levels.
research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth
Targeting the PGD2-DP2 pathway may help treat hair loss.
research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.