January 2015 in “IP Indian journal of clinical and experimental dermatology” This study found statistically significant associations between female androgenetic alopecia and certain components of metabolic syndrome, such as increased waist circumference and hypertriglyceridemia, in the Kashmiri population.
26 citations
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January 2000 in “Hormone research in paediatrics” This review discusses the relationship between hyperandrogenism and insulin resistance in PCOS, focusing on insulin dynamics, molecular mechanisms, genetic studies, and potential long-term treatments, but presents no new clinical results.
1 citations
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January 2001 in “Drug and therapeutics bulletin” This review discusses the management of polycystic ovary syndrome in women and reports no new clinical results.
June 2026 in “International Journal of Research in Medical Sciences” This study compared the adverse effects of baricitinib and methotrexate in treating severe alopecia areata and found baricitinib to have a better safety profile, though it was associated with increased cholesterol, triglyceride, and LDL levels.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case presentation highlights a 26-year-old woman with PCOS, metabolic syndrome, and prediabetes, emphasizing the importance of early recognition and multidisciplinary management to prevent long-term metabolic complications.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case study details a 26-year-old woman diagnosed with PCOS and metabolic syndrome, highlighting the importance of early recognition and multidisciplinary management to improve reproductive and metabolic health outcomes.
2 citations
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March 2026 in “Journal of Dermatological Treatment” This study found that JAK inhibitors used to treat alopecia areata have varied safety profiles, with different adverse events associated with each drug; tofacitinib and ruxolitinib had earlier onset of events, while baricitinib and ritlecitinib showed distinct delayed patterns.
222 citations
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September 2016 in “JCI insight” This research overview highlights that although JAK inhibitors show promise as potential treatments for alopecia areata based on recent insights into the disease mechanism, their efficacy has not yet been thoroughly evaluated in a systematic manner.
January 2026 in “Medicine” This study found that elevated LDL-C levels increased the risk of developing androgenic alopecia, whereas HDL-C levels showed no significant effect.
1 citations
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March 1995 in “Pharmacoepidemiology and drug safety” This study found that female isotretinoin users who also took oral contraceptives were more likely to experience elevated triglyceride or cholesterol levels.
May 2025 in “International Journal of Trichology” This study found that in males with androgenetic alopecia, greater severity was significantly associated with elevated total cholesterol and triglyceride levels, suggesting a need for cardiovascular risk screening.
This study found that patients with lichen planopilaris exhibit a higher pro-atherogenic lipid profile and elevated atherogenic indexes, suggesting a need for increased cardiovascular and lipid monitoring in these individuals.
This study found that in men with androgenetic alopecia, elevated triglycerides were the only factor consistently associated with the condition, suggesting a potential link between AGA and lipid metabolism, although other hormonal, metabolic, and sleep factors were not significantly different after propensity score matching.
17 citations
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January 2014 in “Journal of Clinical and Diagnostic Research” This study found that patients with oral lichen planus and oral lichenoid reactions have higher levels of serum cholesterol and LDL-C than healthy individuals, suggesting a potential elevated risk for cardiovascular disease.
January 2026 in “Egyptian Journal of Dermatology and Venerology” This study found that androgenetic alopecia is associated with insulin resistance, elevated adipokines levels, and dyslipidemia in males, while female patients generally maintained a normal hormonal profile.
February 2026 in “International Journal of Advanced Biochemistry Research” This study reports that dogs with dermatoses linked to hypothyroidism displayed a significant incidence of specific haematological and biochemical alterations, such as elevated cholesterol and triglyceride levels and reduced thyroid hormones, compared to healthy dogs, with Labrador Retrievers showing the highest breed predisposition.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
December 2025 in “Medicine” This study suggests potential causal links between blood levels of glutamine, citric acid, glucose, various lipids, and lipoproteins with alopecia areata, finding glutamine may have a protective effect and noting no evidence of reverse causality. Further research is needed to validate these associations.
October 2023 in “Pakistan Journal of Medical & Health Sciences” In this study examining male patients with androgenetic alopecia, 63.1% were found to have dyslipidemia, with more severe hair loss significantly associated with higher lipid abnormalities, suggesting a link to cardiovascular risk factors.
June 2026 in “Biomolecules and Biomedicine” This study found that women with PCOS had higher levels of serum phoenixin isoforms, which correlated with reproductive and metabolic markers, suggesting these isoforms may have a potential diagnostic role.
January 2023 in “Integrative Journal of Medical Sciences” This report presents a case of a child with hypothyroidism and poorly controlled type 1 diabetes developing both Mauriac syndrome and Van Wyk–Grumbach syndrome, two rare complications.
March 2025 in “Journal of Pakistan Association of Dermatologists” This study observed that 62.7% of men with androgenetic alopecia had abnormal blood lipid levels, suggesting the importance of assessing lipid profiles in these individuals for early detection of cardiovascular and metabolic risks.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
175 citations
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April 1982 in “Journal of The American Academy of Dermatology” This study found that oral isotretinoin achieved good to excellent clinical results in treating severe inflammatory acne, severe rosacea, and gram-negative folliculitis.
March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that androgenic alopecia is highly prevalent in women with PCOS, suggesting early dermatological screening could help identify related metabolic and psychosocial risks.
29 citations
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February 2016 in “International Journal of Dermatology” This study found that patients with lichen planus were significantly more likely to have dyslipidemia, particularly with higher triglyceride levels.
29 citations
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January 2009 in “Gynecological Endocrinology” This study found that women with polycystic ovary syndrome have significantly higher plasma levels of thrombin-activatable fibrinolysis inhibitor and other hemostatic markers compared to age- and BMI-matched healthy controls.
7 citations
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May 2019 in “Journal of the Formosan Medical Association” This study found that overweight women with polycystic ovary syndrome carrying the HSD3B1 1245C allele had an increased presence of female pattern hair loss compared to those with the wild-type genotype.
6 citations
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February 2015 in “Anais Brasileiros de Dermatologia” This study found that patients with mycosis fungoides have higher levels of cardiovascular risk markers, suggesting an increased cardiovascular risk in this group compared to healthy controls.
5 citations
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April 2014 in “Journal of Obstetrics and Gynaecology Research” This study found that young women with PCOS had normal thyroid function but showed alterations in lipid metabolism, which may predispose unmarried women in this group to cardiovascular diseases.