6 citations
,
May 2003 in “PubMed” This study found that DNA is present at low levels in human hair shafts, with higher amounts near the root, and that its levels decrease after surfactant washing and colorant treatments.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
46 citations
,
January 2009 in “Textile Research Journal” This study presents a DNA-analytical method that can reliably identify and differentiate cashmere, fine wool, yak, and camel hair fibers in both untreated and processed samples.
29 citations
,
October 2017 in “Journal of proteomics” This study found that specific proteins associated with fiber structure, hair growth, and fatty acid synthesis, including the DSC2 gene, may influence wool and hair characteristics in sheep and goats.
129 citations
,
October 2017 in “BMC Genomics” This study identified potential ceRNA regulatory networks in cashmere goat hair follicle cycling, expanding understanding of lncRNA and miRNA biology and annotation of the goat genome.
74 citations
,
October 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study discovered nine human type I hair keratin genes, including a transcribed pseudogene, in a 190 kbp genomic region, revealing three gene subclusters based on sequence homologies.
40 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the S100A3 gene is exclusively expressed in hair follicle cells differentiating into hair shaft components in mice, suggesting its important role in hair formation.
27 citations
,
April 2011 in “International journal of legal medicine” This study reports that the completeness of DNA degradation in hair during cornification varies among individuals and affects the success rates of forensic hair DNA analysis.
20 citations
,
June 2012 in “British Journal of Dermatology” This study discusses the proteomic profile associated with hair damage but does not report new experimental findings.
19 citations
,
August 1999 in “European journal of endocrinology” This study concluded that neither basal nor ACTH-stimulated 17-OHP concentrations effectively indicate carrier status for 21-hydroxylase deficiency among Slovenian hyperandrogenic women, recommending molecular analysis of the CYP21 gene for reliable screening.
19 citations
,
March 1961 in “Nature” A fatty acid/protein complex in human hair helps protect it from damage.
18 citations
,
February 2006 in “Genomics” A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
13 citations
,
June 2024 in “BMC Genomics” This study found distinct expression patterns of various transcription types during hair follicle morphogenesis, providing a foundation for understanding hair development mechanisms and aiding selective breeding for desirable wool traits in a specific breed.
12 citations
,
January 2018 in “Journal of Clinical Laboratory Analysis” This study found that IL-18 rs187238 and rs1946518 single nucleotide polymorphisms were associated with increased susceptibility to alopecia areata in a Turkish population.
11 citations
,
August 2024 in “Nature Communications” In this study, researchers observed that quiescent mouse embryonic fibroblasts showed reduced glycolysis but increased TCA cycle flux and mitochondrial respiration, with these changes linked to metabolic reprogramming involving yes-associated protein inhibition and malate cycle modulation, which supports extracellular matrix protein synthesis.
11 citations
,
April 2017 in “Journal of The European Academy of Dermatology and Venereology” This study found that long non-coding RNAs are differentially expressed in androgenetic alopecia, suggesting potential roles in its development and novel targets for prevention and treatment.
10 citations
,
May 2020 in “International Journal of Molecular Sciences” This study suggests that human hair follicles may serve as a model for molecular analysis of ABCA4 gene splice-site variants, facilitating research into the pathogenicity of ABCA4 retinopathies.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
8 citations
,
July 2020 in “BMC genomics” In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.
6 citations
,
May 2022 in “Frontiers in physiology” This study suggests that an in ovo injection of CHIR-99021 promoted feather growth and follicle development in goose embryos by activating the Wnt signaling pathway.
6 citations
,
May 2020 in “Scientific reports” In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.
5 citations
,
May 2024 in “BMC Genomics” This study analyzed the transcriptome of the Tianzhu white yak, identifying differential transcripts that shed light on the molecular mechanisms influencing hair length growth variation in this species.
5 citations
,
September 2021 in “Frontiers in Cell and Developmental Biology” This study found that 3D-cultured dermal papilla cells more accurately mimic in vivo conditions compared to 2D cultures, enhancing our understanding of molecular mechanisms in androgen-induced alopecia.
4 citations
,
July 2022 in “Scientific reports” This study observed significant differences in hair and cashmere properties among three goat breeds in Southwest China, noting better quality cashmere in Inner Mongolia cashmere goats and their crossbreed compared to Dazu black goats.
3 citations
,
February 2011 in “Journal of Biomedical Research/Journal of biomedical research” This study identified a novel mutation, R430Q in the KRT86 gene, in a Han family with monilethrix, which may contribute to the disease's pathogenic mechanism.
1 citations
,
December 2024 in “BMC Genomics” This study used transcriptome analysis to explore the genetic mechanisms behind the development and seasonal variation of nuptial pads in R. chensinensis, identifying key genes and processes that suggest the pads' development involves complex regulatory pathways, particularly those related to cell cycle and hormone synthesis.
1 citations
,
January 2023 in “Burns and trauma” This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.
This study reported that pentoxifylline-loaded liposomes, optimized using a statistical design method, achieved a maximum encapsulation efficiency of 84.23% and a controlled 72-hour drug release, potentially improving therapeutic delivery of the drug with limited bioavailability.
January 2026 in “Veterinary Sciences” In this study, researchers found that significant transcriptomic changes occur in the skin of Dezhou donkey foals as they age from newborns to one year old, involving gene expression shifts that may enhance skin barrier function and hair follicle development, while reducing collagen synthesis.
December 2025 in “Agriculture” In this research, sequencing the chloroplast genomes of 10 Sansevieria trifasciata cultivars allowed the identification of a trnT-psbD deletion marker capable of distinguishing closely related species, and highlighted evolutionary links with Dracaena, contributing molecular tools for taxonomy and phylogenetic studies in Asparagaceae.