4 citations
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December 1995 in “Anthropologischer Anzeiger” This study reports that electrophoretic patterns of hair keratins are more similar among family members than unrelated individuals, potentially aiding genetic studies.
1 citations
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February 1989 in “PubMed” In this study, human hair-carboxymethylated protein analysis showed that weathering for over 2.5 years can obscure electrophoretic patterns, while cosmetic treatments did not cause significant changes.
10 citations
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January 1989 in “Archives of Dermatological Research” The method effectively analyzes human hair proteins, especially nonfilamentous ones.
March 1990 in “Journal of Dermatological Science” 5 citations
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November 2003 in “PubMed” This study found that chemical and photochemical oxidative processes modify the main classes of proteins in hair, confirmed through microspectrophotometric, fluorescence microscopy, and electrophoretic methods.
2 citations
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November 1996 in “PubMed” In this study, a "frequent profile" of hair proteins was observed in 180 of 182 individuals, showing consistent electrophoretic bands characteristic of keratins, with rare deviations in two samples.
8 citations
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January 2015 in “Genetics and molecular research” This study identified four proteins that differ between Type III and non-Type III hair in Yangtze River Delta white goats, contributing to understanding the development of high-quality brush hair.
7 citations
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January 1986 in “Prenatal Diagnosis” This study demonstrated that biochemical analysis of proteins from fetal skin biopsies is feasible, potentially enhancing prenatal diagnostic capabilities for protein-related disorders.
47 citations
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September 2004 in “Journal of Biological Chemistry” This study provides evidence supporting a regulatory relationship between the transcriptional regulator Hoxc13 and Krtap16 genes, which are crucial for proper hair growth in mice.
1 citations
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September 1986 in “Journal of the Forensic Science Society” This study found that hair root sheaths can be accurately typed for erythrocyte acid phosphatase, adenylate kinase, and adenosine deaminase, consistent with blood typing results from the same donors.
This study found that both AB(0) antigens and keratin phenotype can be determined from the same hair fragment using specific protein extraction and analysis methods.
April 2020 in “International Journal of Cosmetic Science” This study found that improved protein extraction methods enhanced the resolution of hair proteins on gels, but differences in protein abundance between curly and straight Japanese women’s hair were minimal and unlikely to affect hair structure.
13 citations
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March 2019 in “PLoS ONE” In this study, the authors developed a modified alkaline-based proteomics protocol that improved the reproducibility of detecting hair proteins, potentially aiding future biomarker discovery.
22 citations
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January 2020 in “PeerJ” This study suggests that keratin peptide signatures in human hair shafts could potentially be used to distinguish gender and ethnicity, though further research on a larger scale is needed.
61 citations
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August 1993 in “PubMed” This study found that solid basal cell epitheliomas and the outer root sheath of human hair follicles display nearly identical cytokeratin profiles, suggesting a potential origin connection.
17 citations
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December 2002 in “Biochemical and biophysical research communications” This study reports on the biochemical characteristics of S100A3 protein in human hair cuticle, notably finding its N-terminal methionine is acetylated and has a slightly lower isoelectric point compared to the recombinant version.
2 citations
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August 1987 in “Analytical Biochemistry” This study introduced a method to isolate and separate microfibrillar proteins from human hair, identifying previously undetected glycine- and tyrosine-rich proteins.
14 citations
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April 2008 in “PROTEOMICS” This study suggests that the down-regulation of 14-3-3 proteins in wild-type keratinocytes, absent in Smad4 mutant keratinocytes, might contribute to the failure of hair follicles to initiate catagen in Smad4 knockout mice.
7 citations
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February 1982 in “Australian Journal of Biological Sciences” This study observed that cell aggregates formed rapidly in cultures of rat hair follicle cells, with proteins showing hair cortical keratin but not synthesizing it as anticipated.
January 1993 in “Nihon Chikusan Gakkaiho” This research found that a monoclonal antibody (MAb 17) specifically reacts with certain subunits of trichocyte keratin in rats, and discovered that trichocyte keratin expression in hair and whiskers begins at different embryonic stages.
1 citations
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January 2014 in “Sen'i Gakkaishi” This study developed a quantitative method using SDS-PAGE and MALDI-TOF mass spectroscopy to accurately determine animal species from hair fibers, validated against standard samples and optical microscopy.
15 citations
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January 1987 in “Electrophoresis” This study found that electrophoretic keratin typing of head hair can identify specific polypeptide patterns, suggesting potential applications in genetic and forensic investigations.
14 citations
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May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.
11 citations
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January 1987 in “Electrophoresis” This study found that keratin phenotypes were consistent across different types of hair from the same individual, allowing for successful keratin typing following ABH blood group determination.
60 citations
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December 2005 in “Biomedical Papers” This article reviews hair analysis for drug detection and its applications in various fields, but reports no new research findings, emphasizing the need to consider the method's complexities and potential pitfalls.
24 citations
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April 2020 in “Cells” This study in cashmere goats found that DNA methylation levels were lower during hair follicle differentiation compared to induction, suggesting it plays a critical role in gene regulation for hair morphogenesis.
23 citations
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February 2015 in “International Journal of Molecular Sciences” This study found that colchicine treatment significantly reduced hair fiber elongation in cultured hair follicles and altered protein expression and activity in dermal papilla cells, suggesting a role for the ubiquitin-proteasome system in its effects.
18 citations
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January 2006 in “Analytical Sciences” This study found that the FIA-amperometric method for minoxidil quantification in pharmaceutical preparations provided accurate results comparable to the conventional UV technique, indicating no systematic errors.
17 citations
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November 2017 in “Asian-Australasian journal of animal sciences” This study found that mutations in certain keratin genes significantly affect wool traits in Chinese Merino sheep, suggesting these genes could be important for sheep breeding to improve wool quality.