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The Rotterdam Study aims to understand various diseases in older adults.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Current treatments for alopecia show no significant long-term benefits.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Finasteride helps hair growth but may cause sexual side effects.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Too much androgen can cause hair loss; finasteride may help.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.