June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
October 2017 in “Anesthesia and Pain Medicine” This report observed that repeated stellate ganglion blocks over six years were associated with improved skin elasticity, increased water content, and more hair follicles on the treated side of a patient's face.
March 2016 in “The Korean Society of Beauty and Art” This study found that using a hair-hardener improved hair thickness, amino acid content, surface condition, tensile strength, and wave efficiency without causing any allergic reactions in participants.
January 2015 in “Springer eBooks” Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
January 2011 in “Zhongguo shiyong fuke yu chanke zazhi” This study concludes that hormone therapy can significantly improve skin hydration, elasticity, thickness, and reduce wrinkles by modulating various skin cells through estrogen receptors.
June 2006 in “Experimental dermatology” This paper reviews potential animal models for studying hidradenitis suppurativa, specifically suggesting that certain mouse models with genetic mutations might be useful, but it reports no new experimental findings.
January 2000 in “Elsevier eBooks” Menopause can cause skin to become dry, less elastic, and more wrinkled due to lower estrogen levels.
June 1996 in “Journal of Dermatological Science” Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.
This article reviews how environmental factors and aging contribute to skin and hair changes, including wrinkling, dryness, pigmentation changes, and hair thinning, but reports no new research findings.
22 citations
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July 2024 in “Archives of Plastic Surgery” This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.
22 citations
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June 1980 in “International Journal of Dermatology” The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
July 2025 in “Journal of Investigative Dermatology” Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.
18 citations
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February 2005 in “Facial plastic surgery” This article reviews techniques for rejuvenating the lower face, neck, and jawline using newer cosmetic interventions and reports no new clinical results.
2 citations
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September 2017 Laser Lax is a new tool that measures scalp looseness accurately and comfortably.
1 citations
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January 1997 in “Skin Pharmacology and Physiology” In this study, researchers found a significant decrease in the modulus of elasticity of hair shafts in premature neonates compared to full-term ones, potentially due to differences in disulphide bonds or microfibril arrangement.
July 2026 in “Discover Food” This review critically examines scientific evidence on the health benefits of rosemary bioactives, finding potential in managing age-related diseases and skin aging conditions, and discusses their application in functional foods and aromatherapy, along with associated safety concerns.
January 2010 in “DR-NTU (Nanyang Technological University)” This study found that exposure to chlorine significantly reduced tensile properties in human hair compared to normal, while dyeing only affected some properties but not all.
2 citations
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September 2023 in “Aging” In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.
December 2025 in “Frontiers in Nutrition” This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.
December 2025 in “Journal of Drug Discovery and Therapeutics” This review discusses spanlastics, advanced elastic vesicles used in drug delivery to enhance bioavailability of poorly soluble drugs, offering improved stability and targeted delivery compared to traditional systems like liposomes and nanoparticles, thus reducing side effects and enhancing therapeutic outcomes.
1 citations
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August 2024 in “PubMed” This study demonstrated that carboxytherapy significantly increased epidermal and dermal thickness, improved collagen and elastin organization, and enhanced expression of TGF-β1 and VEGF in older skin.
April 2024 in “Current research in nutrition and food science” This study found that a food supplement improved skin moisturization, elasticity, and thickness, reduced telogen hair density, and enhanced nail status in women with mild-to-moderate aging signs after 84 days.
47 citations
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September 2011 in “Acta biomaterialia” This study observed that increasing the γ-kerateine content in meta-kerateine materials led to reduced elasticity, solidity, and hydrolytic stability, and decreased hepatocyte attachment support.
27 citations
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July 2020 in “Stem Cells International” This study observed that while PRP therapy increased inflammation and fibrosis in photoaged skin, ADSCs therapy showed promising antiaging effects by promoting elastin and fibrillin formation and remodeling the dermis.
3 citations
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June 2023 in “Journal of cosmetic dermatology” This study found that a topical cream containing CBD and EPA reduced signs of extrinsic skin aging, including wrinkle volume and skin elasticity, in clinical and laboratory settings.
1 citations
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May 2017 in “Asian journal of medical sciences” This study found that dietary supplementation with collagen, chondroitin sulfate, low-molecular weight hyaluronic acid, Pycnogenol®, and coenzyme Q10 significantly improved skin hydration, elasticity, nail hardness, and hair condition in patients with age-related dermatological changes after 12 weeks.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.
November 2025 in “Quality in Sport” This review found that hydrolyzed collagen supplementation, particularly marine collagen, improves skin hydration, elasticity, and density while strengthening hair and nails, especially when paired with vitamin C and trace elements; however, more studies are necessary to evaluate long-term efficacy across different sources and demographics.
This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.