This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
69 citations
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December 2016 in “Facial plastic surgery” This review discusses the anatomical and histological characteristics of facial fat compartments and reports no new clinical results, emphasizing a need for further research on their role in facial aging.
79 citations
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January 2015 in “Journal of Materials Chemistry B” This review discusses the development and future prospects of biomaterials for in situ tissue regeneration but reports no new research results; it underscores the importance of biomaterials in addressing tissue defects.
68 citations
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March 2019 in “Advanced Healthcare Materials” This review assesses the benefits and limitations of various supramolecular hydrogels, including polymeric and peptide-based types, for wound healing, but reports no new clinical results.
64 citations
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May 2019 in “Materials Science and Engineering: C” This review outlines the development, applications, and challenges of microneedle-based drug delivery from 2000-2019, particularly highlighting fabrication techniques, but reports no new clinical results.
45 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews factors affecting follicular unit extraction, emphasizing the need to tailor procedures to individual patient characteristics, but reports no new experimental findings.
38 citations
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June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.
34 citations
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October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
23 citations
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January 2018 in “Elsevier eBooks” This chapter reviews formulation principles for creating cosmetic nanoemulsions and applications targeting skin and hair care, but does not present new experimental results.
19 citations
,
November 2017 in “Journal of Pharmaceutical Sciences” This research investigated aqueous alginate-based hydrogels for delivering minoxidil and reported that using hydroxypropyl-β-cyclodextrin (HP-β-CD) with molar substitution 0.65 significantly enhanced minoxidil's solubility and skin permeability without damaging the epidermis, suggesting potential as an alternative to commercial minoxidil solutions.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” This study evaluated new aqueous gel formulations of minoxidil without irritants and found that the calcium alginate gel showed the best performance in terms of drug release and skin permeation.
16 citations
,
July 2020 in “Advanced functional materials” This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.
11 citations
,
February 2019 in “Frontiers in Physiology” This review explores the complex interrelationships among different properties of natural hair fibers and underscores the need for a holistic taxonomy to improve data interpretation across disciplines, but it reports no new experimental results.
10 citations
,
September 2024 in “Journal of Nanobiotechnology” This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.
9 citations
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December 2024 in “Nano Research” In a study on diabetic mice, researchers developed a protein-based hydrogel that leverages zinc ions and the natural compound phellopterin to promote cutaneous nerve regeneration, angiogenesis, and tissue remodeling in diabetic wounds, highlighting its potential for advanced wound therapy.
9 citations
,
July 2018 in “Acta biomaterialia” This study reports a good correlation between the curvature of human eyelashes and the displacement of the neutral axis, influenced by the non-uniform thickness of the outer cuticle layer.
3 citations
,
January 2024 in “Materials advances” This article reviews the properties of cellulose nanocrystals for sustainable development but presents no new experimental results.
1 citations
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February 2025 in “Notulae Scientia Biologicae” In this study, researchers developed an in-situ gel formulation of antibacterial Levofloxacin for the eye, which showed prolonged drug release, increased residence time, and effective antibacterial action, suggesting it may be a safe and effective ocular delivery system for antibiotics.
1 citations
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April 2015 in “Current problems in dermatology” The document concludes that the trichogram is a useful tool for diagnosing hair loss and suggests semi-organ cultures for practical trichological research.
This study found that depleting fibroblasts in the skin does not affect the proliferative capacity of epidermal stem cells at various ages, suggesting robust compensatory mechanisms maintain skin functionality despite these cellular changes.
February 2026 in “Bioimpacts” This review discusses advancements and challenges in using 3D bioprinting for diabetic foot ulcer treatments, highlighting potential improvements and existing limitations in replicating skin architecture and clinical application.
January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
January 2026 in “Materials Horizons” This article promotes professional recognition in science careers but reports no new research findings.
November 2025 in “Communications Materials” This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.
This review reports that empirical evidence suggests an overlap between Long Covid, chronic fatigue syndrome, and fibromyalgia, highlighting the need for standardized definitions and rigorous methodologies in related research.
February 2025 in “Theranostics” In this study, researchers used 3D bioprinting with skin stem cells and specific hydrogels to create artificial skin that successfully promoted complete wound healing and the regeneration of skin structures, including hair follicles and blood vessels, in mice.
This study found that culturing fibroblasts on stiffer substrates mimicking fibrotic wounds led to an aligned EDA fibronectin matrix with thinner fibers and decreased YAP activity, suggesting disrupted signaling that might be restored to promote regenerative wound repair.
December 2023 in “Biological & pharmaceutical bulletin” This study found that combining lecithin reverse wormlike micelles with isopropyl myristate enhanced the skin permeability of a model hydrophilic drug, facilitated by interactions with sebum in hair follicles.