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Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

Keratins are important for skin cell health and their problems can cause diseases.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.

Prolactin slows down hair growth in mice.

K16 can partially replace K14 but causes hair loss and skin issues.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

Certain drugs that block specific enzymes can help treat prostate diseases.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.