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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Topical minoxidil effectively treats male pattern baldness and prevents hair loss.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.

Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Minoxidil effectively treats female pattern hair loss.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.

Type I interferons play a key role in the development of various skin diseases.

STAT5 activation is crucial for starting the hair growth phase.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

Many women with PCOS have undiagnosed health issues and show different symptoms based on the clinic they visit.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.