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This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

This review discusses the developments in antifungal treatments for dermatophyte infections since 2008, reporting no new oral agents but introducing newer topical options like efinaconazole and tavaborole.

This study found that patients with androgenetic alopecia had higher symptom-related quality of life impairment than those with alopecia areata, with specific influences from age, disease duration, and severity.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

This study found that finasteride alone is highly effective in preventing Candida albicans urinary biofilms and shows synergistic activity with fluconazole in vitro, suggesting potential for further clinical investigation.

This study reports that once-daily oxiconazole cream effectively achieves mycologic and clinical cures for various fungal infections, with success rates of at least 80% in patients.

This study concluded that topical ketoconazole is effective and safe for treating superficial fungal infections and has potential for new dermatologic uses despite concerns over oral administration's adverse effects.

This study found that once-daily oxiconazole cream effectively treats tinea infections, achieving at least 80% cure rates, and shows comparable efficacy to other antifungal creams with similar tolerability.

In this case study of a 64-year-old woman with kerion celsi caused by Microsporum canis, treatment with the oral antifungal fosravuconazole resulted in symptom resolution without scarring or side effects over 12 weeks, suggesting its potential effectiveness for various dermatomycoses.

This case report describes a 20-year-old female with favus caused by T. schöenleinii, which initially improved with antifungal treatment but recurred due to poor adherence, underscoring favus as an ongoing health issue in Turkey.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.

Isoconazole nitrate stays effective in skin and hair follicles for up to two weeks after use.

In this study, terbinafine reached high concentrations in stratum corneum and sebum after oral administration, with drug levels remaining above fungicidal concentrations for over three weeks.

This paper suggests that ketoconazole 2% shampoo may enhance finasteride's effectiveness in treating androgenetic alopecia by more completely inhibiting the dihydrotestosterone pathway.

This study found that the novel antifungal emulsion NB-002 demonstrated significant antifungal activity and nail clearing in patients with distal subungual onychomycosis involving ≤50% of the nail.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

This case report describes the first known instance of fixed drug eruption linked to finasteride, confirmed through an oral challenge test that reproduced symptoms at the same skin site.

This study found that fluconazole was associated with telogen effluvium in both a rat model and human patients, although retinoic acid levels were not identified as a causal factor.

This case report suggests that anidulafungin may be associated with hair loss, highlighting the need for physicians to monitor this potential adverse effect.

This study found that finasteride delivered through a nano-transferosomal gel showed improved penetration through skin layers compared to a conventional gel, suggesting a potential alternative for oral administration.

In this study, researchers evaluated 27 drugs for antifungal activity against Cryptococcus strains and found that some antiparasitics and antidepressants showed potential by reducing fungal growth and capsule size, with particular enhancements when combined with fluconazole.

This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.

P-3074 effectively blocks scalp DHT better than oral finasteride.

This study found that continuous itraconazole therapy was more effective than pulse therapy for treating tinea capitis caused by Microsporum ferrugineum, with a higher cumulative cure rate and no significant adverse effects.