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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Some herbs show promise as antiandrogenic agents.

Hair transplants look natural, but the best method is debated, and PRP shows promise for hair regrowth.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

Researchers identified specific genes that are important for mouse skin cell development and healing.

PCPA induces hypersexual behavior in male rats regardless of age or castration status.

The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.

Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.