research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
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research Effect of Finasteride 5 mg (Proscar) on Acne and Alopecia in Female Patients with Normal Serum Levels of Free Testosterone
Finasteride improves acne and hair loss in women with normal testosterone.
research Presence of Polycystic Ovary Syndrome Is Associated with Longer Anogenital Distance in Adult Mediterranean Women
Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
research Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior
Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Analysis of 1,25-Dihydroxyvitamin D3 Receptors in Basal Cell Carcinomas
Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
research Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Skin Aging as a Mechanical Phenomenon: The Main Weak Links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
research Congenital Hair Loss Disorders: Rare, But Not Too Rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
research Psychodermatology: Emotional Factors and Treatment Approaches
The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.
research Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness
Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Iron Plays a Certain Role in Patterned Hair Loss
Iron deficiency may contribute to hair loss.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Polycystic Ovary Syndrome (PCOS): French Endocrine Society Recommendations for Diagnosis and Management
The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.
research Minoxidil: Hope for the Bald?
Minoxidil helps some bald men, but most lose hair again when stopping.
research Adipose Mesenchymal Stem Cells Combined with Platelet-Rich Plasma Accelerate Diabetic Wound Healing by Modulating the Notch Pathway
Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
research Nonsurgical Management of Facial Masculinization and Feminization
Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.
research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability
Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
research Self-Assembling Peptide Hydrogel Scaffolds Support Stem Cell-Based Hair Follicle Regeneration
Peptide hydrogel scaffolds help grow new hair follicles using stem cells.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research Antiandrogen And Hormonal Treatment Of Acne
Certain hormone treatments can improve acne and related conditions in women.
research Hirsutism
Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.
research Recent Advances in Thiasteroids Chemistry
New sulfur-containing steroid analogs show promise for more targeted medical treatments.
research Surgical Approach to Adolescent Obesity
Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
research The Human Gut Chemical Landscape Predicts Microbe-Mediated Biotransformation of Foods and Drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
research Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia Along with Dermoscopic Pre- and Post-Treatment Evaluation
PRP with microneedling effectively treats hair loss, and dermoscopy helps evaluate results.