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Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

PRP injections may improve hair thickness and density in female hair loss patients.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.

Decomposed tritiated thymidine is less accurate for DNA tracing, and hair changes can indicate malnutrition.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Chemotherapy often causes patterned hair loss, with some scalp areas more resistant to hair loss than others.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

PRP injections improve hair density and thickness in women with hair loss.

Patients with PCOS rate their hirsutism higher than clinicians, and these self-ratings are more closely related to their quality of life and risk of depression.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.