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      The Evaluation and Management of Hirsutism

      research The evaluation and management of hirsutism*1

      195 citations , May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology”
      This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
      Herbal Therapy in Dermatology

      research Herbal Therapy in Dermatology

      191 citations , February 2002 in “Archives of Dermatology”
      This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
      Biology of Estrogens in Skin: Implications for Skin Aging

      research Biology of estrogens in skin: implications for skin aging

      187 citations , December 2005 in “Experimental Dermatology”
      This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.
      COVID-19 and Sex Differences: Mechanisms and Biomarkers

      research COVID-19 and Sex Differences

      185 citations , August 2020 in “Mayo Clinic Proceedings”
      This review discusses biological sex differences in COVID-19 outcomes and reports no new clinical results; it identifies a need for studies to clarify how sex influences disease progression.
      Adverse Effects of Opioid Analgesic Drugs

      research ADVERSE EFFECTS OF OPIOID ANALGESIC DRUGS

      183 citations , January 1987 in “British Journal of Anaesthesia”
      This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.
      The Role of Hair Follicles in the Percutaneous Absorption of Caffeine

      research The role of hair follicles in the percutaneous absorption of caffeine

      182 citations , December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology”
      This study demonstrated that hair follicles significantly expedite the absorption of caffeine through the skin compared to interfollicular pathways.
      Trichoscopy Update 2011

      research Trichoscopy update 2011

      178 citations , December 2011 in “Journal of Dermatological Case Reports”
      This review discusses the application of trichoscopy in diagnosing various hair and scalp diseases and reports no new clinical results; the authors emphasize its role as a non-invasive diagnostic tool.
      Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

      176 citations , August 2000 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
      Why Some Women Look Young for Their Age

      research Why Some Women Look Young for Their Age

      175 citations , November 2009 in “PLOS ONE”
      This study found that both genetic and environmental factors influence appearance-related aging in women, with skin wrinkling, hair graying, and sun damage significantly affecting perceived age more than chronological age.
      Androgenetic Alopecia: Pathogenesis and Potential for Therapy

      research Androgenetic alopecia: pathogenesis and potential for therapy

      174 citations , November 2002 in “Expert Reviews in Molecular Medicine”
      This review discusses the genetic factors contributing to androgenetic alopecia and highlights the potential for developing more effective therapies based on recent discoveries, but reports no new clinical results.
      The Effects of Estrogens on Linear Bone Growth

      research The effects of oestrogens on linear bone growth

      173 citations , May 2001 in “Human reproduction update”
      This review discusses the role of oestrogens in stimulating growth hormone secretion and influencing linear bone growth in children, and reports no new clinical results; the authors suggest that oestrogens play a key role in pubertal growth spurts for both genders.
      Fetal Alcohol Syndrome: Current Status of Pathogenesis

      research Fetal Alcohol Syndrome: Current Status of Pathogenesis

      171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”
      The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      Hirsutism and Acne in Polycystic Ovary Syndrome

      research Hirsutism and acne in polycystic ovary syndrome

      169 citations , August 2004 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology”
      This article discusses treatments for hirsutism and acne in women with polycystic ovary syndrome, suggesting that lower doses of current medications maintain efficacy while reducing cost and side effects, but reports no new clinical results.
      Anthracycline Analogs: The Past, Present, And Future

      research Anthracycline analogs The past, present, and future

      168 citations , December 1986 in “Cancer Chemotherapy and Pharmacology”
      Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
      Endocrinology of Transgender Medicine

      research Endocrinology of Transgender Medicine

      166 citations , October 2018 in “Endocrine Reviews”
      This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
      The Human Tri-Peptide GHK and Tissue Remodeling

      research The human tri-peptide GHK and tissue remodeling

      165 citations , January 2008 in “Journal of biomaterials science. Polymer ed.”
      This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.