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This study investigated dermal fibroblasts in mouse skin using single-cell RNA sequencing and identified signaling pathways that influence adipogenesis, finding that IL-1-NF-κB promotes, while WNT-β-catenin inhibits, the adipogenic potential of these cells, with implications for wound healing and scar formation.

This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.

This study identified a distinct CD49fhigh mesenchymal stem cell subpopulation in the dermis that supports hair follicle development and maintenance via Notch signaling activation.

This study examined aging hair follicle stem cells in mice and found that inflammation reduction in dermal white adipose tissue can stimulate regenerative behavior, highlighting its role in hair follicle aging.

This review discusses the impact of lifestyle interventions, including diet and probiotics, on weight and metabolic health in women with PCOS, but reports no new clinical results.

This review outlines the current state of stem cell therapy in dermatology, highlighting its potential for treating a variety of skin disorders and conditions, while emphasizing the need for further controlled studies to standardize treatment and fully understand its efficacy and limitations.

This article discusses the impact of hyperandrogenism in polycystic ovary syndrome on women's physical and mental health, but it reports no new experimental findings.

Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.

This study found that the acyl-CoA binding protein is essential for the production of very long chain free fatty acids in the stratum corneum and maintaining normal epidermal barrier function in mice.

This study found that using ectopic expression of CD24 is a promising approach for selecting genetically modified human epidermal stem cells for safe cutaneous gene therapy in cancer-prone conditions.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

In this study, ectopic Wnt10b-mediated β-catenin activation in hair follicles resulted in larger regenerating anagen hair structures, an effect modulated by the Wnt inhibitor DKK1.

This case report highlights a rare instance of severe multi-organ involvement following a single dose of methotrexate for ectopic pregnancy, requiring intensive care but ultimately successfully treated with leucovorin and supportive care.

This study reports that Lef1 plays a crucial role in promoting bulge stem cell differentiation towards hair fate by activating β-catenin and downstream signaling pathways during hair follicle development.

This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.

This study found that androgen receptor activation in adult mouse skin reduces β-catenin-induced hair follicle growth and sebaceous gland conversion, highlighting its role in stem cell fate decisions.

The study characterized the transcriptional changes in porcine SKP cells transitioning to fibroblast-like cells, indicating potential roles for specific signaling pathways in this cell fate transition.

This study found that cellular retinoic acid-binding proteins and fatty acid-binding proteins are dynamically expressed in skin development and respond differently to retinoic acid, β-catenin, and Notch signaling.

This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.

The document describes various skin conditions, their features, and treatments but lacks detailed study size information.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This study found that finasteride treatment of male rats led to changes in their male offspring's testicular gene expression, potentially affecting sperm function in response to odorant-like signals.

This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.

This study reveals an antagonistic competition between BMP and Wnt signaling within stem cells, influencing their fate towards hair germ characteristics based on the BMP/Wnt activity ratio.

This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.

This study found that targeting connective tissue sheath contraction with an MLCK inhibitor may improve hair growth in androgenetic alopecia by reducing premature hair regression caused by ectopic apoptosis of hair follicle progenitor cells.

This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.

This review discusses the role of Wnt/β‐catenin signaling in stem and cancer stem cell maintenance and its involvement in the development and regeneration of various organs, but reports no new experimental results.

This review examines skin symptoms, diagnosis, and treatment of zinc deficiency in children, proposing a classification system but reporting no new clinical results.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.