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Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

The study found that the protein Dkk4 helps regulate hair growth by controlling Wnt signaling in mice.

Neonatal hair can help determine drug exposure during pregnancy.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.

Sox21 is crucial for tooth development and enamel formation by preventing cells from changing into a different type.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Mechanical forces are crucial for shaping cells and forming tissues during development.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

Blocking a specific protein signal can make hair grow on mouse nipples.

Edar signaling is crucial for proper hair follicle development and function.

Some hair protein genes evolved early and were adapted for use in hair follicles.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.