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This study found that loss-of-function mutations in the HOXC13 gene cause autosomal-recessive pure hair and nail ectodermal dysplasia, emphasizing its role in hair and nail development.

This review examines the roles of Hedgehog and Gli proteins in mouse embryonic mammary development and suggests that Gli3-repressor-mediated off-state of Hedgehog signaling determines mammary fate over hair follicle fate.

This review discusses the potential applications and challenges of small molecules in regenerative medicine, but it reports no new research findings.

This study found that Msx2-deficient mice exhibit skull and bone formation defects similar to those seen in human MSX2-related conditions, highlighting the gene's importance in skeletal and organ development.

This review discusses the role of TGM3 in skin and hair follicle biology, human tumor pathology, and genetic abnormalities, and reports no novel results; the authors highlight its potential as a cancer diagnostic biomarker.

This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.

In this study, overexpression of secretory phospholipase A2 Group-IIA in transgenic mice led to depletion of hair follicle stem cells and increased differentiation, linked to changes in histone modifications.

In this study, researchers found that AP-2α and AP-2β are critical for maintaining epidermal homeostasis in adult skin, with their combined loss leading to severe skin and hair abnormalities and early skin inflammation due to impaired keratinocyte differentiation.

This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

In this study, researchers used transcriptomics and modeling to uncover previously unknown cell populations and marker genes in developing hair follicles, providing insights into early cell fate establishment and offering tools for further research on skin appendages.

This review discusses potential biomarkers for alopecia and their significance, and while it highlights areas for future research, it reports no new clinical results.

In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.

This study found that deleting the vitamin D receptor from specific stem cells in mouse hair follicles disrupts their ability to regenerate the epidermis after injury, suggesting an essential interaction with the transcription factor p63.

This review discusses the role of activin signaling in hair follicle formation, hair growth cycling, and skin healing, but presents no new clinical findings.

This study describes a protocol for generating hair-bearing skin organoids from human pluripotent stem cells, achieving full complexity resembling fetal skin tissue by day 130 in vitro.

This review discusses recent advancements in skin epigenetics, focusing on how epigenetic mechanisms regulate gene expression during normal skin function and their dysregulation in conditions like skin disorders and cancer, but reports no new clinical results.

This study found that manipulating Wnt/β-catenin signaling in embryonic mammary glands impacted their development, with high activity levels hindering branching and potentially redirecting cells toward hair follicle identity instead of mammary tissue.

This study found that retinoic acid induces epidermal transdifferentiation into mucosal epithelium in both chick and mammalian embryonic skin, involving specific gene expressions and pathways.

This study observed that the loss of H3K9me3, via the ablation of Suv39h1, Suv39h2, and Setdb1 in embryonic mouse epidermis, disrupts skin development processes such as keratinocyte differentiation and hair follicle formation, highlighting H3K9me3's crucial role in epidermal morphogenesis.

This review discusses the development of human skin with a focus on desmosomes, noting the challenges of translating animal model findings to humans due to species differences and limited human sample access.

In this study, researchers found that treating dermal papilla cells with synovial fluid and laser photobiomodulation increases the expression of chondrocyte marker genes, indicating potential promotion of chondrogenic differentiation.

This study highlighted the effectiveness of HT-scCAT-seq as a tool for understanding gene regulation in single cells, offering insights into embryonic skin development and proposing a framework for exploring regulatory mechanisms in various biological and disease contexts.

This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.

This review discusses the critical role of BMP signaling in the development and regulation of skin and hair follicles and notes that further research could aid therapeutic advances; it presents no new clinical results.

A specific gene mutation causes complete hair loss in an Irish Traveller family.

This review discusses the role of peptidylarginine deiminases in skin homeostasis and diseases, particularly in keratinocyte differentiation and hair disorders, but presents no new experimental findings.

In this study, transgenic mice expressing Msx-2 developed flaky skin with hyperproliferation and misalignment in epidermal cells, suggesting Msx-2 plays a role in skin and appendage growth control.

This study reported that deleting the MED1 subunit from the MED complex in keratinocytes resulted in disrupted hair differentiation and cycling, leading to hair loss in mice.

This review discusses ichthyosis with confetti, highlighting its genetic basis, clinical features, diagnostic criteria, and current treatment options but reports no new clinical results.

This article discusses the use of platelet-rich plasma as a supportive treatment for hair loss, emphasizing its potential to enhance hair follicle health and patient satisfaction, but reports no new clinical results.