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The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

New effective scar treatments are urgently needed due to the current options' limited success.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Bioprinting could improve wound healing but needs more development to match real skin.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Estrogen therapy can reduce skin aging but has cancer risks.

Stem cell self-renewal is complex and needs more research for full understanding.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Fat cells in the skin help start healing and form important repair cells after injury.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Skin fat helps with body temperature control and has other active roles in health.

Turing patterns are now recognized as important in developmental biology.