121 citations
,
May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.
118 citations
,
July 2005 in “Journal of Ethnopharmacology” In this study, the aqueous extract of Eclipta alba and its hydrolyzed fraction showed nootropic activity and reduced stress-induced alterations in rats.
64 citations
,
June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
50 citations
,
May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
46 citations
,
August 2019 in “Journal of Ethnopharmacology” This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.
24 citations
,
December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
21 citations
,
November 2021 in “Biomolecules” This review compiles information on traditional uses, phytoconstituents, and biological activities of Eclipta prostrata but reports no new experimental results; the authors call for more studies to understand its pharmacological mechanisms.
13 citations
,
October 2017 in “Biomedicine & Pharmacotherapy” In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.
11 citations
,
May 2021 in “Asian Journal of Pharmaceutical and Clinical Research” This review summarizes the phytomedicinal importance of Eclipta alba in Ayurvedic and folk medicine, particularly its use for hair growth and various biological properties, without reporting new clinical results.
6 citations
,
October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
6 citations
,
January 2022 in “GSC Biological and Pharmaceutical Sciences” This review discusses the ethnobotanical use and bioactivity of Eclipta prostrata, highlighting its potential in treating various conditions and linking its effects to secondary metabolites.
6 citations
,
May 2018 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study found that adjusting plant growth conditions, such as the use of elicitors like yeast extract and methyl jasmonate, increased wedelolactone production in Eclipta alba cell suspension culture.
5 citations
,
October 2018 in “Journal of Drug Delivery and Therapeutics” This study found that Eclipta alba may protect against scopolamine-induced memory deficits in mice by reducing brain acetylcholinestrase activity and oxidative stress.
5 citations
,
May 2016 in “Jahangirnagar University Journal of Biological Sciences” This study demonstrated that the most effective method for inducing multiple shoots and root development in Eclipta alba involved specific concentrations of plant hormones on MS medium, resulting in healthy, flowering plantlets.
4 citations
,
December 2020 in “Natural Product Sciences” This study identified ten compounds from Eclipta prostrata, with some displaying potent inhibitory effects against α-glucosidase and acetylcholinesterase enzymes.
4 citations
,
August 2018 in “International Journal of Current Microbiology and Applied Sciences” This study identified various phytochemicals and compounds in Eclipta prostrata leaves using qualitative tests, FTIR, and GC-MS analysis, highlighting the presence of phytol and squalene among others.
3 citations
,
March 2017 in “International Journal of Ayurvedic Medicine” This review discusses the ethnomedicinal claims, chemical composition, and pharmacological profile of Eclipta alba Hassk., reporting no new clinical results but suggesting future research for traditional medicine validation.
2 citations
,
January 2020 in “Journal of Pharmacognosy and Phytochemistry” This article reviews the medicinal significance of the Eclipta alba plant in India and its therapeutic properties, but reports no new clinical results.
2 citations
,
July 2017 in “Deleted Journal” This review discusses the memory enhancing activity of the ethanolic extract of Eclipta alba and reports no new clinical results.
1 citations
,
July 2022 in “Plant Cell, Tissue and Organ Culture (PCTOC)” This study identified that the biosynthetic pathways for coumestans in Eclipta prostrata are derived from acetate and shikimate pathways, while phenylpropanoid biosynthesis is exclusively from the shikimate pathway.
1 citations
,
November 2023 in “Indian Journal of Science and Technology” In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
1 citations
,
July 2023 in “International Journal of Pharmaceutical Sciences and Drug Research” This study developed an effective and reliable HPTLC method for the simultaneous measurement of linoleic acid and oleanolic acid in Eclipta alba.
1 citations
,
January 2022 This book chapter reviews the taxonomy, traditional uses, pharmacological effects, and safety of Eclipta prostrata, emphasizing its potential therapeutic applications, but it reports no new clinical results.
1 citations
,
January 2020 in “International journal of research in pharmacy and chemistry” This review provides an overview of the ethnomedicinal uses, chemical composition, and pharmacological profile of Eclipta alba Hassk and presents no new clinical findings.
1 citations
,
January 2019 in “International Journal of ChemTech Research” This study reviews the pharmacological properties of the plant Eclipta prostrata, highlighting its potential in treating various conditions including wound healing, diabetes, liver protection, alopecia, gum disease, cancer prevention, bone health, and antimicrobial effects, alongside its traditional use in tropical regions.
This review discusses the traditional use of Eclipta alba in Ayurvedic medicine for liver disorders, hypertension, and notably for stimulating hair growth, but reports no new clinical results.
1 citations
,
January 2017 in “Pharmaceutica Analytica Acta” This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
1 citations
,
January 2016 in “Der pharmacia lettre” This study found that shampoo formulated with Eclipta alba extracts may promote hair growth and act as an antidandruff agent due to its antifungal activity against Malassezia.
1 citations
,
January 2013 in “African Journal of Pharmacy and Pharmacology” This study found that ultrasound assisted microwave extraction was more efficient than other methods for extracting luteolin from Eclipta prostrata, reducing extraction time and simplifying the process.
1 citations
,
January 2012 in “Ancient Science of Life” This study found that the ethanol extract of Eclipta alba significantly reduced gastric lesions and enhanced gastroprotective activity in ulcer-induced rats, suggesting potent antisecretory effects potentially linked to antioxidant properties.