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The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Melatonin-loaded microemulsion could be a promising treatment for hair loss.

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.

The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.

Methotrexate injection site reactions are rare but can be managed by changing injection sites and using topical treatments.

A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.

A patient with patchy hair loss was successfully treated for Tumid Lupus Erythematosus after other treatments failed.

Areata-like lupus can mimic alopecia areata but is a form of cutaneous lupus erythematosus.

Melatonin in a special emulsion can help treat hair loss more effectively.

Porcine skin is very similar to human skin, making it a useful model for research.

Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

COVID-19 can cause various skin issues in children, mostly not severe, with chilblain-like lesions being common, especially in adolescents.

Body hairs can be used in forensic science and toxicology like scalp hair.

A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

Runx3 helps determine hair shape.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

3D imaging shows clearer details of skin structure changes with age.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.