56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
2 citations,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
125 citations,
September 2001 in “The FASEB Journal” Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
42 citations,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.
212 citations,
September 2008 in “Journal of The American Academy of Dermatology” Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
2 citations,
June 2011 in “Journal of clinical and experimental investigations” Oral zinc sulphate is an effective and safe treatment for thallium poisoning, especially for skin and hair symptoms.
June 2011 in “Journal of clinical and experimental investigations” Oral zinc sulphate is an effective and safe treatment for thallium poisoning.
November 2008 in “Medical & surgical dermatology” A device was made in 2008 to measure hair loss severity. Other findings include: frizzy mutation in mice isn't related to Fgfr2, C/EBPx marks preadipocytes, Cyclosporin A speeds up hair growth in mice, blocking plasmin and metalloproteinases hinders healing, hyperbaric oxygen helps ischemic wound healing, amniotic membranes heal wounds better than polyurethane foam, rhVEGF165 from a fibrin matrix improves tissue flap viability and induces VEGF-R2 expression, and bFGF enhances wound healing and reduces scarring in rabbits.
2 citations,
January 2023 in “Pharmaceuticals” Natural products and phytochemicals may help with hair regrowth, but more research is needed.
35 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Intralesional triamcinolone acetonide is effective for treating patchy hair loss, and dermoscopy helps detect treatment response and side effects early.
North American ginseng extract helped regrow hair in balding mice.
April 2016 in “Journal of The American Academy of Dermatology” The study found that severe alopecia areata affects any age, treatments often give temporary results, and some factors predict worse outcomes.
18 citations,
January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
October 2023 in “Dermatology practical & conceptual” Pulse corticosteroids help regrow hair in alopecia areata but have side effects, especially betamethasone.
58 citations,
January 2018 in “International Journal of Women's Dermatology” Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.
8 citations,
June 2020 in “International Journal of Dermatology” Men with early hair loss have lower vitamin D levels.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Men with early baldness often have low vitamin D levels.
1 citations,
April 2016 in “Journal of The American Academy of Dermatology” People with allergies or high eosinophil levels have a higher chance of severe hair loss from alopecia areata, and sudden hair loss can indicate chronic graft-versus-host disease.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
May 2017 in “InTech eBooks” Early treatment of children's hair loss, which can be caused by various factors, is important due to its emotional impact.
April 2020 in “International Journal of Research in Dermatology” Scalp skin conditions are more common in young adults and teenagers, especially males, with itching being the main complaint. The most common conditions are psoriasis and alopecia areata, and these can significantly affect a person's social life due to their psychological impact.
April 2016 in “Journal of The American Academy of Dermatology” People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.
1 citations,
November 1953 in “Archives of Dermatology” The document discusses various challenging skin conditions and their treatments.
26 citations,
October 2020 in “Pediatric Dermatology” Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
50 citations,
March 2000 in “American Journal of Clinical Dermatology” Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.
131 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
14 citations,
January 2017 in “Skin appendage disorders” Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.
1 citations,
January 2015 in “Springer eBooks” The document says a skin condition called alopecia areata causes hair loss and stress, and is treated with strong skin creams, injections, or other therapies, but treatment success varies.