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Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Some children are born with unusually short, fine hair because their hair growth phase is short, but this often gets better by itself during puberty.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.

Sertoliform endometrioid carcinoma of the ovary, though rare, has a good prognosis when treated early.

Hair pulling disorder is treated with therapy and medication; hair loss from tension can be reversed if caught early.

PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.

Low vitamin D levels can significantly contribute to hair loss, especially in women aged 35-45. Correcting these levels early may help prevent and treat this condition.

Male pattern baldness, especially the vertex type, could be an early sign of cardiovascular risk factors like high cholesterol and diabetes.

Men with common hair loss (AGA) are more likely to have metabolic syndrome, which increases heart disease risk. Early screening could help prevent heart disease. More research is needed to understand this relationship better.

Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Early hormones shape sex-specific differences in rat glands.

The conclusion suggests that early signs of hidradenitis suppurativa may start in the hair follicle, with genetic and immune factors playing a role, highlighting the need for more research on the hair follicle's immune system.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Understanding hair follicle anatomy helps diagnose hair disorders.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Understanding skin patterns can help us learn about skin diseases and their treatments.

Acne is a temporary skin imbalance during puberty that often resolves on its own.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

PFAS exposure in adolescence may delay puberty in females.