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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

K16 can partially replace K14 but causes hair loss and skin issues.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Type I interferons play a key role in the development of various skin diseases.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Finasteride negatively affects fish reproduction and gonadal development.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

Sphinganine can reduce hair loss and improve scalp health.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

New hair follicles could be created to treat hair loss.

CRABP1 boosts hair cell growth in Hu sheep by affecting key genes.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.

Genes linked to wool fineness in sheep have been identified.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Laser treatment and synovial fluid can change hair follicle cells to resemble joint cells, with the changes being more significant when both treatments are used together.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.