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PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Testosterone may slow down wound healing and increase inflammation.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.

Hair loss links to higher death risk from diabetes and heart disease; not a direct cause, but a marker for risk factors.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

People with polycystic ovary syndrome may have a higher risk of heart problems due to abnormal nervous system control of their heart and blood pressure.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

People with lichen planus have higher bad cholesterol and lower good cholesterol, increasing their risk for heart disease.

Macrophages are essential for successful skin growth in reconstructive surgery.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Autophagy is important for human hair growth and health.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Using steroids can increase the risk of heart problems.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Minoxidil may cause heart issues in animals and humans.