The researchers observed that in cichlid fishes with different dental structures, tooth replacement accelerated more than three times following tooth extraction, alongside distinct changes in gene expression and cellular interactions over one week, providing insights into tooth regeneration mechanisms in vertebrates.
December 2025 in “Nature Communications” In this study using mouse models, researchers found that elevated IL-17a in aged olfactory epithelium impairs olfactory function, while IL-17a inhibition promotes regeneration and mitigates age-related decline.
November 2025 in “Scientific Reports” This study demonstrates that an AI-based grading framework using a novel area ratio metric improves the accuracy and consistency of male pattern hair loss classification, especially in advanced grades, compared to traditional methods.
In this case report, the authors documented a fatal instance of Stevens-Johnson syndrome in an elderly woman potentially triggered by doxycycline and flucloxacillin, emphasizing the importance of recognizing such rare but severe drug reactions in older patients.
June 2025 in “Veterinární Medicína” In this veterinary study, uveodermatological syndrome in dogs was reported to cause skin depigmentation, alopecia, and eye issues such as granulomatous panuveitis, which leads to complications like cataracts and glaucoma; while immunosuppressive therapy often helps, recurrence and treatment side effects challenging therapeutic management.
October 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the potential use of prostate specific antigen as a diagnostic marker for hyperandrogenism in polycystic ovary syndrome but reports no new clinical results and calls for further research.
January 2021 in “Skin appendage disorders” This review discusses atypical presentations of Brauer nevus, particularly in occipital and mid-frontal areas, and reports a higher occurrence in males, with detection usually at birth.
January 2020 in “Research Portal Denmark” This study concludes that anti-androgenic chemicals causing short anogenital distance in male fetuses also induce a feminized transcriptional profile in the perineum, implicating Wnt and estrogen signaling in the process.
This article provides an overview of conditions that can cause hair loss in dogs and cats and offers guidance on diagnostic approaches, but it presents no new research findings.
January 2019 in “Elsevier eBooks” Early detection and skin biopsies are crucial for treating skin cancer and diagnosing various skin conditions.
July 2018 in “Elsevier eBooks” This article reviews the clinical presentation, diagnosis, and treatment options for discoid lupus erythematosus and reports no new clinical results.
June 2018 in “Acta Scientiae Veterinariae” This study describes three cases of dermatomyositis-like disease in mongrel dogs with compatible clinical findings and outcomes following slightly different treatment protocols.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
This article reviews the spectrum of connective tissue disorders and discusses the role of autoantibodies, particularly in lupus erythematosus, but reports no new findings.
September 2014 in “Journal der Deutschen Dermatologischen Gesellschaft” Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.
January 2014 in “Durham e-Theses (Durham University)” In this study, the activation of Notch1 signaling in keratinocytes was found to play a key role in recruiting immune cells and facilitating skin repair after injury.
In this study of foxes and jackals in Ilam province, Iran, 19.35% of foxes and 17.85% of jackals were found to be infested with ectoparasites, mainly Ctenocephalides canis.
70 citations
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July 2020 in “Pharmacological Reports” This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.
30 citations
,
November 2013 in “PLOS ONE” This study found that androgen/androgen receptor signaling accelerates premature senescence in dermal papilla cells, highlighting a potential target for treating androgenetic alopecia.
35 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the impact of different forms of alopecia on patients with systemic autoimmune diseases and reports no new clinical findings; it emphasizes the need for attentive management of alopecia-related symptoms.
September 2023 in “Curēus” This study found that individuals with alopecia areata showed differences in otoacoustic emissions, suggesting potential links between the condition and auditory dysfunction, with significant gender and age group variations observed in hearing test results.
January 2015 in “Springer eBooks” Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
March 2014 in “Journal of The American Academy of Dermatology” The document lists various dermatology topics, treatments, and diagnostic methods.
1160 citations
,
November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
759 citations
,
February 2009 in “Current Biology” This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.
556 citations
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September 2008 in “Genes & Development” This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.
393 citations
,
November 2000 in “Archives of General Psychiatry” This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.
384 citations
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June 2005 in “Genes & development” This study found that stabilized beta-catenin is crucial for activating stem cell transition from quiescence to proliferation in hair follicles by influencing gene expression within the stem cell niche.
350 citations
,
June 1989 in “The American Journal of Medicine” This study suggests that itraconazole may significantly improve therapy for aspergillosis, with 12 out of 15 evaluable patients responding to the treatment.
349 citations
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January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.