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RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

Exosomes could be a promising way to help repair skin and treat skin disorders.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

Vitamin D receptor is crucial for skin wound healing.

Exosomal miRNAs from stem cells can help improve skin health and delay aging.

Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.

Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Dental pulp stem cells might not reliably become neurons.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.

The essence made from fermented products increased hair growth in mice better than minoxidil.

JAK inhibitors help with skin conditions but need more research on dosing and safety.