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Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Hair in mammals likely evolved from glandular structures, not scales.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The skin microbiome helps heal wounds and can be targeted to improve healing.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

The shape of fibrous scaffolds can improve how stem cells help heal skin.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Poplar seed hairs grow from the placenta at the ovary base, with endoreduplication playing a key role in their development, and share similar cellulose synthesis processes with cotton fibers.

The document concludes that more research is needed to fully understand the causes of PCOS.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

New technologies help us better understand how skin microbes affect skin diseases.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Immune cells are essential for early hair and skin development and healing.

Sweat gland development involves two unique skin cell programs and a temporary skin environment.

Terbinafine is the most effective treatment for tinea capitis, a scalp infection often confused with other conditions.

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

Cudrania tricuspidata and Sargassum fusiforme extracts improved hair growth in mice by affecting growth-related genes.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Fat cells in the skin help start healing and form important repair cells after injury.