research Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice
Exosomes from umbilical cord cells fix hearing loss and damaged ear hair cells in mice.
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research Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year
Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
research Association of Autoimmune Regulator Gene Rs2075876 Variant, but Not Gene Expression, with Alopecia Areata in Males: A Case-Control Study
The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.
research Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia
Age, gender, and hair loss affect scalp characteristics differently in young Caucasian adults.
research Skin Disorders Associated with the COVID-19 Pandemic: A Review
The review found that COVID-19 can cause skin problems, including rashes and issues from wearing PPE, and suggests more research and protective measures for healthcare workers.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Biomacromolecules/Modified Halloysite Composite Hydrogel Used as Multifunctional Wound Dressing
The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.
research Tracing Selection Signatures in the Pig Genome Provides Evidence for Selective Pressures on a Unique Curly Hair Phenotype in Mangalitza
Selective breeding caused the unique curly hair in Mangalitza pigs.
research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Cross-Sectional Quality of Life Assessment in Patients with Androgenetic Alopecia
Hair loss lowers quality of life, causing embarrassment, frustration, and sexual rejection.
research Should We Consider Alternative Therapies to Operative Hysteroscopy for the Treatment of Asherman Syndrome?
Operative hysteroscopy is still the main treatment for Asherman syndrome, but more research is needed on post-surgery methods.
research Frontal Fibrosing Alopecia in Asians: A Retrospective Clinical Study
The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.
research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study
Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.
research Chemically Induced Transformation of Human Dermal Fibroblasts to Hair-Inducing Dermal Papilla-Like Cells
Researchers found a way to turn skin cells into cells that can grow new hair.
research A Histological and Clinical Evaluation of Plasma as a Graft Holding Solution and Its Efficacy in Hair Growth and Graft Survival
Plasma is better than Ringer's lactate for hair graft survival and growth after transplantation.
research The Post-Finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption
Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.
research A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study
A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.
research Cleave But Not Leave: Astrotactin Proteins in Development and Disease
Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.
research Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells
Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
research Frontal Fibrosing Alopecia in Men: Presentations in 12 Cases and a Review of the Literature
FFA in men, often mistaken for other hair loss types, may be more common than thought and needs larger studies for confirmation.
research Lisinopril-Induced Alopecia: A Case Report
Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice
Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
research Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan
Both dermatologists and patients in Japan agree that treatment success for alopecia areata is having 20% or less scalp hair loss.
research Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification
Key genes can rewire networks, changing skin appendage types.
research New Treatments for Hair Loss
Several new treatments for different types of hair loss show promise in improving patient quality of life.
research Hyperandrogenism-Insulin Resistance-Acanthosis Nigricans Syndrome
The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
research Two Cases of Stroke Associated with the Use of Finasteride, an Approved Drug for Male-Pattern Hair Loss in Japan
Finasteride, a hair loss medication, may be linked to stroke in young men.
research Testosterone- and Cortisol-Secreting Adrenocortical Oncocytoma: An Unusual Cause of Hirsutism
A woman's excessive hair growth was caused by a rare benign tumor in her adrenal gland, which was successfully removed.