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The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Researchers found 15 new genetic links to skin traits in Japanese women.

Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Exosomes from human skin cells can stimulate hair growth and could potentially be used for treating hair loss.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

Improving the environment and cell interactions is key for creating human hair in the lab.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Finasteride helps reduce heart issues and improves heart function.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.