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This study found that deslorelin implants can effectively reduce estradiol levels and support hair regrowth in neutered ferrets with hyperoestrogenism caused by nodular hyperplasia of the adrenocortex.

This study found that both declining levels of the neurosteroid THP and increasing levels of estradiol before puberty trigger maximal expression of α4βδ GABAA receptors in the CA1 hippocampus of female mice.

This study found that the E2-ANGPT2 pathway is involved in hair follicle regulation and that ANGPT2 treatment increased hair density in modeled female pattern hair loss, suggesting potential therapeutic use.

This study found that 17beta-estradiol enhanced allergy responses in certain age groups of female mice and inhibited thymus involution and regeneration after contact hypersensitivity.

This study found that progesterone and its metabolite, allopregnanolone, provided anti-anxiety and anti-depressive effects in female mice, potentially independent of nuclear progestin receptors but requiring 5α-reduction and estradiol's influence on brain-derived neurotrophic factor.

In this study, Leonuri Herba alkaloids significantly reduced prostate hyperplasia indicators and improved urinary parameters in hormone-induced model rats.

This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.

This study identified genes potentially involved in hair and cashmere growth in the Laiwu black goat, highlighting specific gene expression differences between hair-growing and hairless skin.

This study found that Arc/Arg3.1 expression in hippocampal neurons is regulated by sex steroids in a sex-dependent manner, with E2 increasing expression in females and DHT in males.

This study suggests that estrogen regulates vitamin A metabolism in skin tissues in a sex-dependent manner, which may have implications for treating acne, hair loss, and skin immunity.

This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.

This study found that estradiol significantly reduces cisplatin-induced cochlear hair cell death in mice, likely by activating Nrf2 and phase II detoxification enzymes.

This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.

This study found that among men with Benign Prostatic Hyperplasia, treatment with the 5α-reductase inhibitor finasteride for three months significantly reduced levels of dihydrotestosterone and estradiol, hormones involved in prostate enlargement, without altering follicle-stimulating hormone or luteinizing hormone levels.

Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.

This study observed that in infertile females, those with PCOS had higher BMI, increased LH levels, and altered LH/FSH ratios compared to non-PCOS females, although no significant correlation was found between BMI and hormone levels among the PCOS group.

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

This study found that sex hormone-binding globulin promotes facial aging, while sex steroid hormones such as testosterone and estradiol inhibit it, with growth hormone levels showing no significant effect.

This study reported that immortalizing human dermal papilla cells using HPV16 E6/E7 oncogenes increased their proliferation and maintained their hair follicle formation capability, potentially facilitating in vitro hair growth and regeneration research.

This study found that recombinant oleosin-hFGF5 expressed in Arabidopsis can inhibit hair regeneration by decreasing the proliferation of hair follicle epithelial cells.

This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.

This study found that serum GPER-1 levels may serve as a biomarker for differentiating androgenetic alopecia from telogen effluvium and healthy controls, although its ability to distinguish between AGA and TE is limited.

This study established reference values for nine fertility hormones important in diagnosing and monitoring PCOS in Pakistani and other subcontinent populations.

This study found that teenage girls born via assisted reproductive technologies displayed premature development of secondary sexual characteristics and elevated hormone levels, indicating late precocious puberty and androgen excess.

This case study observed that in four middle-aged men with ejaculation disorders, therapy with human chorionic gonadotropin (hCG) alone or combined with recombinant follicle-stimulating hormone (rFSH) improved sexual desire, semen volume, and various other symptoms, although some experienced elevated estradiol levels and hair loss.

This study observed that in spontaneously hypertensive rats, testosterone's effects on endothelium-dependent vasodilation involved reduced nitric oxide levels, increased oxidative stress, and greater reliance on endothelium-dependent hyperpolarization, with variations in these responses noted when testosterone was combined with either anastrozole or finasteride.

In this retrospective study, researchers observed that infertile patients with PCOS have significantly different serum levels of certain hormones, specifically higher AMH and LH, and lower E2 and FSH, compared to infertile women without PCOS.

This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).

Estrogen may help improve COVID-19 outcomes, especially in women.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.