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This study found that Polygonum multiflorum radix ethanol extract may promote melanin synthesis, potentially helping to turn gray hair back to black by enhancing antioxidant activity and increasing tyrosinase expression.

This study found that Physcion from Polygonum multiflorum may be an effective natural 5α-reductase inhibitor for treating androgenic alopecia by enhancing hair growth and improving follicle morphology in laboratory settings.

This review discusses the molecular biology, diagnosis, and pathology of epidermolysis bullosa in animals and reports no new clinical findings.

This study found that methylprednisolone pulse therapy may be an effective treatment option for patients with severe multifocal alopecia areata, particularly those experiencing their first episode.

This case report describes a miniature dachshund with pustular dermatitis and other symptoms, developing pemphigus foliaceus after receiving afoxolaner, which was effectively managed with prednisone and cyclosporine.

This review explored the causes of hair graying and evaluated how plant-derived extracts and phytochemicals might alleviate it, noting that certain compounds showed potential in enhancing melanocyte function, reducing oxidative stress, and influencing stress-related pathways based on experimental evidence.

This study found that emodin from Polygonum multiflorum showed 5alpha-reductase inhibitory activity, which was more potent than alizarin but less potent than riboflavin.

This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.

This article discusses the familiarity of identifying male androgenetic alopecia but presents no new research findings.

This study found that individuals with seborrheic alopecia had significant disruptions in their scalp microbiome, marked by imbalances in certain bacteria and fungi, and that a 12-week herbal shampoo intervention helped restore microbial diversity and improve clinical symptoms.

This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.

This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.

This review summarizes the pharmacology, mechanisms, and clinical efficacy of topical immunotherapy for alopecia areata but reports no new clinical results.

This article reports a case of Rowell syndrome in a woman with chronic cutaneous lupus erythematosus that appeared to be triggered by COVID-19 infection, suggesting a potential connection.

This review discusses the role of teledermatology during the COVID-19 pandemic, highlighting the practical challenges and opportunities in diagnosing skin diseases in low-income countries, and reports no new clinical results.

This review discusses the increasing reports of rare cutaneous side effects from topical imiquimod, aiming to inform physicians and dermatologists about its potential adverse effects as its use expands.

There are two main types of alopecia areata with different severity, and diagnosis is made through clinical examination and trichoscopy, influencing treatment choices.

Skin symptoms could help in early COVID-19 diagnosis but more research is needed to confirm their reliability.

This study found that components in the kernel of Prunus mira Koehne, such as vitamin E and β-sitosterol, may promote hair growth in mice, possibly involving the Wnt/β-catenin signaling pathway.

This review highlights the potential of nanotechnology-based formulations in hair care and treatment, emphasizing how these innovative materials can enhance the stability, efficacy, and safety of active compounds while addressing the limitations of conventional formulations.

This systematic review of pulse corticosteroid therapy for alopecia areata found relatively low complete response rates, but responders experienced low relapse rates, indicating potential benefits for patients with favorable prognostic factors.

This study found that methotrexate may be an effective and safe treatment option for severe alopecia areata, with better regrowth results when combined with corticosteroids.

This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.

This study found that topical application of TSG from Polygonum multiflorum promoted hair regrowth in depilated mice, potentially through the inhibition of apoptosis-related proteins.

This case report describes the first documented occurrence of pili torti in a healthy young adult cat, marked by noninflammatory and nonpruritic symmetrical multifocal alopecia.

This case report describes an 11-month-old infant with Biotinidase deficiency who exhibited multifocal seizures, neuroregression, alopecia, and skin issues, highlighting prompt diagnosis and the dramatic clinical response to biotin treatment.

In this report, a case of steroid-resistant multifocal alopecia areata was successfully treated with topical bimatoprost, suggesting it may be a promising alternative therapy.

In this study, a dog with canine pattern alopecia showed improved multifocal alopecia and general hair regrowth after 3 months of melatonin treatment.

This open-label study suggests that combining valproate, lamotrigine, and a benzodiazepine can significantly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies.

The authors concluded that thymoma-associated paraneoplastic syndrome in cats may manifest as noninflammatory alopecia instead of exfoliative dermatitis, and should be considered when diagnosing multifocal noninflammatory alopecia.