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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.