research Whole Exome Sequencing in Alopecia Areata Identifies Rare Variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
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research Independent DSG4 Frameshift Variants in Cats with Hair Shaft Dystrophy
Cats with abnormal hair had DSG4 gene changes causing hair problems.
research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes
Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
research Cepharanthine: An Update of Its Mode of Action, Pharmacological Properties, and Medical Applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Alopecia Universalis: A Review of Over 750 Cases of Nonscarring Alopecia
Alopecia can be linked to autoimmune issues, vitiligo, nail problems, and sometimes cancer treatments.
research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research Nail Matrix Pathology in Cronkhite–Canada Syndrome: The First Case Report
Inflammation may cause nail issues in Cronkhite–Canada Syndrome.
research The Relevance of Collagen XVII Expression in Epidermal Differentiation and Proliferation
Collagen XVII is crucial for skin cell growth and nail health.
research A Patient With Cronkhite-Canada Syndrome Whose Entire Digestive Tract Was Examined Endoscopically
Prednisolone improved symptoms in a woman with Cronkhite-Canada syndrome, but regular screenings are needed due to cancer risk.
research An Inherited Nail Dystrophy Principally Affecting the Great Toenails
The document concludes that an inherited nail condition often improves on its own, and spironolactone effectively treats acne in women.
research JAK Inhibition in the Treatment of Alopecia Areata: A Promising New Dawn?
JAK inhibitors are a promising new treatment for hair loss and nail problems in alopecia areata.
research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Recovery of Nail Dystrophy: Potential New Therapeutic Indication of Tofacitinib
Tofacitinib may help treat nail dystrophy, especially when other treatments fail.
research Prognostic Factors That Affect the Response to Topical Treatment in Patchy Alopecia Areata
Certain factors like allergies, nail problems, and hair loss patterns can predict how well someone with patchy hair loss will respond to skin cream treatments.
research Retrospective Review of Diphencyprone in the Treatment of Alopecia Areata
Diphencyprone helped most patients with alopecia areata regrow some hair.
research Zinc: An Undervalued Microelement in Research and Treatment
Zinc is important for health and its supplementation may help treat various conditions.
research Olmsted Syndrome: A Rare Keratinization Disorder
Olmsted syndrome is a rare skin disorder causing thickened skin and other symptoms.
research Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and Literature Review of 13 Cases in Korea
First Korean case of Cronkhite-Canada syndrome with colon cancer and serrated adenoma.
research Cronkhite-Canada Syndrome: A Rare Disease Presenting with Dermatological and Gastrointestinal Manifestations
A patient with Cronkhite-Canada syndrome improved with nutritional support and steroids, but early diagnosis is key due to high mortality.
research Alopecia Areata: Prognostic Factors
Alopecia areata is unpredictable, with limited treatment effectiveness, especially in severe cases.
research Impact of Coronavirus in a Dermatology Outpatient Clinic: A Single-Center Retrospective Study
The COVID-19 pandemic changed the types of skin conditions seen at a clinic, with fewer patients and varying numbers of specific conditions.
research Contents Volume 2, 2016
The document discusses various nail and hair disorders and their treatments.
research Clinical Case of Alopecia Totalis in Pediatric Practice
An 11-year-old child with total hair loss may have a genetic autoimmune disease, and the outlook for hair regrowth is not good.
research Androgenic Pattern Presentation of Scarring and Inflammatory Alopecia
Many people diagnosed with androgenic alopecia might actually have hidden scarring or inflammation.
research Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis
FOXN1 gene variants cause low T cells and immune issues from birth.
research A Generalized Reticulate Eruption with Scarring Alopecia, Vulvovaginitis, Keratoderma, and 20-Nail Dystrophy in a 70-Year-Old Woman
Treatment improved some symptoms but not all.
research Ruxolitinib Rescues Multiorgan Clinical Autoimmunity in Patients With APS-1
Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
research A Case of Red Lunulae After Hematopoietic Stem Cell Transplantation
Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.