29 citations,
October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
January 2008 in “American journal of clinical dermatology” 132 citations,
August 2008 in “Development” Dlx3 is essential for hair growth and regeneration.
234 citations,
November 2009 in “American journal of human genetics” Common variants in the Trichohyalin gene are linked to straight hair in Europeans.
188 citations,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
86 citations,
June 2018 in “Cochrane library” Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.
42 citations,
December 2011 in “The journal of immunology/The Journal of immunology” RANKL causes lymph nodes to grow by making certain cells multiply.
16 citations,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
15 citations,
June 2019 in “eLife” Activin A and follistatin control when hair cells develop in mouse ears.
13 citations,
September 2022 in “Materials & design” The new patch for treating mouth sores releases medicine slowly, sticks well, and helps healing without the side effects of current creams.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology” DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
July 2023 in “Current Issues in Molecular Biology” Escin may help treat hair loss by boosting a specific cell growth pathway.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
April 2018 in “Journal of Investigative Dermatology” Watching, not removing, skin growths with moderate atypia and positive edges is okay; patients may get melanoma elsewhere, especially if they've had it before.
39 citations,
July 1997 in “American Journal of Medical Genetics” The gene for Clouston syndrome in a large Indian family is located in the 13q11-q12.1 region.
32 citations,
December 1969 in “The Lancet” Children with marasmus have more resting hair follicles and thinner, less pigmented hair, showing long-term malnutrition.
20 citations,
November 1968 in “The Lancet” Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.
16 citations,
January 1989 in “Springer eBooks” Cyproterone acetate effectively treats female hair loss by increasing healthy hair and decreasing unhealthy hair, but doesn't change hair thickness.
6 citations,
May 1987 in “Acta dermato-venereologica” Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.
July 2023 in “Veterinary pathology” White-tailed deer can get a hair loss condition that might make them more vulnerable to environmental threats.
19 citations,
October 1988 in “Clinics in dermatology” Retinoids might help hair grow and improve hair loss treatments.
1 citations,
January 2018 in “Indian dermatology online journal” Early diagnosis and genetic evaluation of ADULT syndrome are crucial to reduce stress and medical costs.
OCT can effectively screen and diagnose various medical conditions non-invasively.
15 citations,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
August 2013 in “Gastroenterology” A 60-year-old man with Cronkhite-Canada syndrome improved with treatment, but the condition has a high mortality rate and a risk of colorectal cancer.
August 2015 in “Advances in Small Animal Medicine and Surgery” Low-level laser therapy may help regrow hair in dogs with non-inflammatory hair loss.
15 citations,
June 2011 in “British Journal of Dermatology” No link found between aromatase gene and female hair loss.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.