25 citations
,
January 2013 in “Colloids and surfaces. B, Biointerfaces” This study found that melanin granules in black human hair are key dyeing regions for oxidative hair coloring, as confirmed by nanoscale mass spectrometry analysis detecting deuterium ions.
13 citations
,
January 1995 in “Journal of the American Institute for Conservation” This study introduced a new method for extracting red mordant dyes from wool fibers that preserved the fibers for further analysis and allowed for spectrophotometric examination of the dyes' absorption curves.
9 citations
,
November 2000 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study demonstrated that dyeing can enhance the absorption coefficient of hair follicle tissues for selective photodestruction within human skin and hair follicles.
9 citations
,
November 2006 in “Journal of Microscopy” This study using an apertureless scanning near-field optical microscope found that dye restricted to hair's periphery remains mainly on the surface and in the endocuticle.
6 citations
,
May 2020 in “Molecules/Molecules online/Molecules annual” This study found that while yak belly hair is chemically similar to human hair, its higher porosity and lower mechanical strength limit its usefulness as a substitute in hair dye development.
5 citations
,
April 2018 in “Chem” This study introduced a novel graphene-based hair dye that is non-reactive, non-invasive, and eliminates toxic chemicals, while providing durable color, antistatic properties, and efficient heat dissipation, even after 30 washes.
5 citations
,
January 2011 in “International Journal of Cosmetic Science” This study found that 1,2,3,4-tetrahydroquinoline derivatives, particularly N-methyl-7-amino-1,2,3,4-tetrahydroquinoline, may be excellent blue dye candidates for human hair, offering superior color purity, stability, and fastness compared to 2,3-dihydroindoles.
4 citations
,
August 2016 in “PubMed” This study analyzed how oxidative hair dye leaches from pigmented and nonpigmented hair during wash cycles, finding that melanin influences the dye deposition and leaching processes.
1 citations
,
January 2002 in “Springer eBooks”
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study examined how different hair dye processes affect hair structure at a molecular level, finding that oxidative dyes increase keratin porosity more than non-oxidative dyes, and highlighted emerging technology aimed at reducing hair damage while preserving color quality.
June 2021 in “Research Square (Research Square)” This study found that dyed chitin nanofibers maintain color and mechanical properties when reinforcing resins, allowing color addition and strength improvement while retaining transparency.
January 2006 in “东华大学学报:英文版” This study found that treating yak hair fibers with low-temperature plasma and microwaves weakened the scale structure and significantly improved dyeability.
98 citations
,
November 2002 in “Contact Dermatitis” This study found that adverse reactions to para-phenylenediamine in hair dye, including severe allergic contact dermatitis, may be more common than currently reported and often misdiagnosed.
84 citations
,
April 2015 in “Cosmetics” This review discusses various types of hair dyes, their mechanisms of action, molecular structures, application methods, and formulation aspects, but reports no new research findings.
66 citations
,
February 1985 in “Archives of dermatological research” Hair dyes penetrate the scalp very minimally, less than 1%.
63 citations
,
February 2017 in “ACS biomaterials science & engineering” In this study, polydopamine emerged as a safe and effective alternative to traditional hair dyes like PPD for dyeing gray hair permanently, showing resistance to detergents and causing less toxicity and hair loss in mice.
40 citations
,
February 2002 in “International Journal of Dermatology” In this study, hair damaged by permanent dye showed signs of recovery over time, with near complete restoration to its original state after eight weeks.
36 citations
,
July 2004 in “Journal of Controlled Release” This study demonstrates that confocal laser scanning microscopy can effectively visualize the rapid diffusion and penetration pathway of a dye into the hair follicle in fresh human scalp skin.
33 citations
,
January 2017 in “Psychoneuroendocrinology” This study of Danish women found no evidence linking hair cortisol concentration to hair dyeing status or the frequency of hair washing.
27 citations
,
February 2003 in “Cell and Tissue Research” This study found that FM dyes are effective markers for tracing live Merkel cells in in vitro experiments, as they remain visible for at least seven days and highlight cell shape better than quinacrine.
22 citations
,
November 2010 in “Toxicological & Environmental Chemistry Reviews” In this study, higher concentrations of Pb, Cd, Cu, and Zn were found in the hair of smokers and users of hair dyes compared to non-smokers and those with undyed hair.
21 citations
,
October 2014 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses the role of hair dyes in cosmetic dermatology, their effects on hair and scalp health, and the importance of dermatologists understanding potential side effects; it reports no new findings.
20 citations
,
June 2011 in “ISRN Dermatology (Print)” This case report describes a woman experiencing severe hair loss due to allergic contact dermatitis from a hair dye containing PPD.
19 citations
,
January 2012 in “Annals of Dermatology” This article recommends creating a system to educate users about the ingredients and side effects of hair coloring products and does not report new research findings.
16 citations
,
October 2009 in “Xenobiotica” This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.
13 citations
,
February 2008 This study reports that the newly developed natural dye-based sindoor is safe for skin application and offers a non-toxic alternative to synthetic dye-based sindoor.
12 citations
,
May 2013 in “International Journal of Dermatology” This study found that a non-ionic ethosomal carrier system significantly improved the delivery and adsorption of black tea extracts onto hair surfaces in vitro, suggesting its potential as a hair dye and protective agent.
9 citations
,
July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
9 citations
,
January 2010 This study reports that a 100% herbal hair dye composed primarily of Cymphomandra betacea, Tagetes erecta, and Aloe vera gel provides permanent hair color without causing hair damage, loss, or skin irritation compared to synthetic dyes.
8 citations
,
November 2019 in “International Journal of Morphology” This study found that using henna dye positively affected hair cuticula pattern and diameters compared to undyed hair, though the degree of change may vary based on hair phenotype and condition prior to treatment.